| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Cormorant Asset Management Bihua Chen | 2,976,000 | $71,692 | 4.36% | |
| 2. | Sectoral Asset Management Jerome Pfund And Michael Sjostrom | 996,983 | $24,017 | -34% | 4.14% |
| 3. | DAFNA Capital Management Nathan Fischel | 169,800 | $4,090 | 1.53% | |
| 4. | Clough Capital Partners Charles Clough | 518,834 | $12,499 | -13% | 1.03% |
| 5. | Eversept Partners Kamran Moghtaderi | 79,509 | $1,915 | -33% | 0.59% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $29.71 | 11,699 | Officer | 11,699 | 2019-08-29 | Filing | |
| $17.00 | 441,176 | Large Shareholder | 12,015,802 | 2019-03-11 | Filing | |
| $19.84 | 40,000 | Large Shareholder | 11,574,626 | 2018-09-21 | Filing | |
| $19.43 | 21,724 | Large Shareholder | 11,534,626 | 2018-09-20 | Filing | |
| $18.79 | 19,599 | Large Shareholder | 11,512,902 | 2018-09-20 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $27.28 | 5,000 | Officer, Director | 1,011,793 | 2019-11-15 | Filing | |
| $26.61 | 3,524 | Officer, Director | 1,016,793 | 2019-10-15 | Filing | |
| $25.59 | 1,476 | Officer, Director | 1,020,317 | 2019-10-15 | Filing | |
| $25.64 | 1,010 | Officer | 881,743 | 2019-09-25 | Filing | |
| $25.24 | 20,531 | Officer | 882,753 | 2019-09-25 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 705,923 | $17,005 | 0.42% | |
| 2. | 21,309 | $513 | 0.16% | |
| 3. | 12,700 | $306 | 0.15% | |
| 4. | 47,900 | $1,153 | 0.14% | |
| 5. | 434,700 | $10 | 0.12% |
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