| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Aisling Capital Dennis Purcell | 1,240,000 | $25,966 | -38% | 57.34% |
| 2. | Palo Alto Investors William Leland Edwards | 3,471,740 | $72,698 | -10% | 4.84% |
| 3. | Dorset Management David M. Knott | 55,990 | $1,173 | -3% | 0.49% |
| 4. | Deerfield Management James E. Flynn | 339,480 | $7,109 | 0.28% | |
| 5. | Hudson Bay Capital Management Sander Gerber | 440,000 | $9,214 | 0.25% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.57 | 1,550 | Officer | 33,574 | 2019-09-18 | Filing | |
| $27.56 | 50 | Officer, Director | 63,650 | 2018-11-19 | Filing | |
| $27.56 | 3,600 | Officer, Director | 63,600 | 2018-11-19 | Filing | |
| $30.41 | 1,600 | Officer | 19,485 | 2018-06-13 | Filing | |
| $32.00 | 9,375 | Large Shareholder | 16,651 | 2018-02-22 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $35.00 | 20,000 | Officer | 21,250 | 2020-01-02 | Filing | |
| $33.03 | 10,000 | Officer | 45,668 | 2019-12-26 | Filing | |
| $30.04 | 20,000 | Officer | 21,250 | 2019-12-09 | Filing | |
| $30.04 | 40,000 | Officer | 9,375 | 2018-11-19 | Filing | |
| $30.83 | 29,457 | Officer, Director | 315,308 | 2018-06-11 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 150,000 | $5,021 | 0.55% | |
| 2. | 23,958 | $802 | 0.07% | |
| 3. | 5,000 | $167 | 0% | |
| 4. | 0 | $0 | 0% | |
| 5. | 2,532 | $82 | 0% |
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