Arcus Biosciences Inc. (NYSE:RCUS) is one of billionaire Steve Cohen’s 10 small-cap stock picks with huge upside potential. On October 6, Arcus Biosciences Inc. (NYSE:RCUS) announced encouraging data for its kidney cancer drug casdatifan.
The HIF-2a inhibitor demonstrated positive results across all efficacy measures in the Phase 1/1b study. In trials involving 121 patients across four immunotherapy cohorts, the candidate drug achieved a median progression-free survival of 12.2 months.
Casdatifan showed an acceptable safety profile with anemia and hypoxia. During the trials, only 9% of the patients discontinued the treatment due to adverse events.
“Even when we analyzed pooled data for the 121 patients treated with casdatifan monotherapy, casdatifan showed a confirmed ORR of 31% and a median PFS of 12.2 months, which is meaningfully longer than published data from studies with the only marketed HIF-2a inhibitor and for TKIs alone in a similar patient population and setting,” said Richard Markus, M.D., Ph.D., chief medical officer at Arcus Biosciences.
Arcus Biosciences Inc. is a clinical-stage Biopharmaceutical Company that discovers and develops novel combination therapies for cancer, focusing on both small molecules and antibodies to address unmet medical needs.
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This article is originally published at Insider Monkey.
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