5 Most Profitable S&P 500 Stocks to Invest In

In this article, we will list the 5 Most Profitable S&P 500 Stocks to Invest In. Please visit 12 Most Profitable S&P 500 Stocks to Invest In if you would like to see the extended list and the methodology behind it.

5. Blackstone Inc. (NYSE:BX)

On June 23, 2026, Sunstone Hotel (SHO) announced a definitive agreement to sell the 821-room Hyatt Regency San Francisco to funds affiliated with Blackstone Inc. (NYSE:BX) Real Estate for a gross sale price of $279M, or about $340,000 per key. The price represents a 21.4x multiple on Hotel Adjusted EBITDA and a 3.5% cap rate on Hotel Net Operating Income for the trailing twelve-month period ended May 31. Sunstone expects the transaction to close in late July or early August and plans to provide more details, including the expected impact on its full-year outlook, in its quarterly earnings release in early August.

On June 16, Blackstone Credit & Insurance announced the launch of SablePointe Credit Strategies, a new platform supporting origination, underwriting, and portfolio management in asset-based lending. SablePointe hired James Garlick, former co-founder of Wingspire, as President to lead the platform’s buildout and growth. Headquartered in Alpharetta, Georgia, SablePointe will support BXCI in sourcing, structuring, and managing senior secured asset-based and first-out credit facilities for corporate borrowers.

On June 10, BizLink signed a share purchase agreement to acquire Interplex Datacom, a division of Ennovi, a portfolio company under certain funds managed by Blackstone, for an enterprise value of $850M, plus up to $50M in contingent consideration. The all-cash transaction is expected to close in the second half of 2026, subject to customary closing conditions.

Blackstone Inc. (NYSE:BX) is an alternative asset management firm specializing in private equity, venture capital, real estate, hedge fund solutions, credit, secondary funds of funds, public debt and equity, and multi-asset class strategies.