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Wilmot B. Harkey And Daniel Mack

A recent filing with the US Securities and Exchange Commission showed that Wilmot B. Harkey and Daniel Mack‘s Nantahala Capital Management holds a long position in ArQule, Inc. (NASDAQ:ARQL). The 13G filing showed that Nantahala has amassed 9.67 million shares of ArQule, higher than the 5.91 million shares it disclosed in its latest 13F filing. Following the increase, Nantahala holds 13.4% of ArQule’s common stock.

ArQule, Inc. (NASDAQ:ARQL) shareholders have witnessed a decrease in support from the world’s most elite money managers lately. At the end of the fourth quarter, a total of nine of the hedge funds tracked by Insider Monkey were bullish on this stock, a change of -10% from one quarter earlier.

When looking at the institutional investors followed by Insider Monkey, First Eagle Investment Management holds the biggest position in ArQule, Inc. (NASDAQ:ARQL). First Eagle Investment Management has a $18.9 million position in the stock, comprising less than 0.1%% of its 13F portfolio. The second largest stake is held by Biotechnology Value Fund / BVF Inc, led by Mark Lampert, holding a $14.8 million position; the fund has 2.5% of its 13F portfolio invested in the stock. Other professional money managers that are bullish contain Wilmot B. Harkey and Daniel Mack’s Nantahala Capital Management, Jim Simons’ Renaissance Technologies and D. E. Shaw’s D E Shaw.

You can access the original SEC filing by clicking here.

Ownership Summary Table

Name Sole Voting Power Shared Voting Power Sole Dispositive Power Shared Dispositive Power Aggregate Amount Owned Power Percent of Class
Nantahala Capital Management 0 9,668,880 0 9,668,880 9,668,880 13.4%
Wilmot B. Harkey( 0 9,668,880 0 9,668,880 9,668,880 13.4%
Daniel Mack( 0 9,668,880 0 9,668,880 9,668,880 13.4%
Wilmot B. Harkey And Daniel Mack
Wilmot B. Harkey And Daniel Mack
Nantahala Capital Management

Page 1 of 7 SEC Filing



Washington, D.C.



Under the Securities
Exchange Act of 1934

No. 1)*

ArQule, Inc.

(Name of Issuer)

Common Stock,
$0.01 par value

(Title of Class of


(CUSIP Number)

February 29, 2016

(Date of Event which
Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to
which this Schedule is filed:

x  Rule 13d-1(b)
¨  Rule 13d-1(c)
¨  Rule 13d-1(d)

*The remainder of this cover page shall
be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any
subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required on the remainder
of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of
1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions
of the Act (however, see the Notes).

Continued on following pages

Page 1 of 7 Pages

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