| Insider | Symbol | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
| Officer, Director | ALNY | $363.55 | 301 | $109,428.55 | 82,918 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $362.38 | 464 | $168,144.32 | 83,219 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $361.45 | 624 | $225,544.80 | 83,683 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $360.22 | 980 | $353,015.60 | 84,307 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $359.14 | 537 | $192,858.18 | 85,287 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $358.18 | 778 | $278,664.04 | 85,824 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $357.17 | 607 | $216,802.19 | 86,602 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $356.09 | 263 | $93,651.67 | 87,209 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $355.16 | 269 | $95,538.04 | 87,472 | 2026-01-12 | Filing |
| Officer, Director | ALNY | $353.95 | 247 | $87,425.65 | 87,741 | 2026-01-12 | Filing |
| Officer | ALNY | $377.82 | 27 | $10,201.14 | 57,465 | 2026-01-12 | Filing |
| Officer | ALNY | $375.65 | 34 | $12,772.10 | 57,492 | 2026-01-12 | Filing |
| Officer | ALNY | $374.44 | 25 | $9,361.00 | 57,526 | 2026-01-12 | Filing |
| Officer | ALNY | $372.46 | 6 | $2,234.76 | 57,551 | 2026-01-12 | Filing |
| Officer | ALNY | $370.87 | 36 | $13,351.32 | 57,557 | 2026-01-12 | Filing |
| Officer | ALNY | $369.48 | 73 | $26,972.04 | 57,593 | 2026-01-12 | Filing |
| Officer | ALNY | $368.62 | 170 | $62,665.40 | 57,666 | 2026-01-12 | Filing |
| Officer | ALNY | $367.40 | 76 | $27,922.40 | 57,836 | 2026-01-12 | Filing |
| Officer | ALNY | $366.41 | 92 | $33,709.72 | 57,912 | 2026-01-12 | Filing |
| Officer | ALNY | $365.56 | 405 | $148,051.80 | 58,004 | 2026-01-12 | Filing |