Spyre Therapeutics Inc. (SYRE)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Fmr Llc	9,038,553	$145,837,052	0.01%
2.	Fairmount Funds Management Llc	4,018,101	$64,832,060	10.06%
3.	Rtw Investments, Llc	3,621,996	$58,440,905	0.89%
4.	Blackrock, Inc.	3,572,674	$57,645,096	0%
5.	Vanguard Group Inc	2,898,267	$46,763,538	0%