Spyre Therapeutics Inc. (SYRE)

Warren Buffett

Berkshire Hathaway

$293,447,417,000

David Einhorn

Greenlight Capital

$1,491,303,000

George Soros

Soros Fund Management

$5,416,602,000

Jim Simons

Renaissance Technologies

$77,426,184,000

Leon Cooperman

Omega Advisors

$1,886,381,000

Carl Icahn

Icahn Capital LP

$22,521,664,000

Steve Cohen

Point72 Asset Management

$22,767,998,000

John Paulson

Paulson & Co

$3,510,256,000

David Tepper

Appaloosa Management LP

$4,198,712,000

Paul Tudor Jones

Tudor Investment Corp

$6,160,740,000