| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Siren L.L.C. Raymond Debbane | 9,250,005 | $297,387,661 | 16.78% | |
| 2. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 5,612,896 | $180,454,606 | 32.18% | |
| 3. | Redmile Group Jeremy Green | 4,398,281 | $141,404,734 | -4% | 13.37% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 2,583,371 | $83,055,378 | -5% | 0.51% |
| 5. | Adage Capital Management Phill Gross And Robert Atchinson | 2,018,000 | $64,878,700 | +27% | 0.12% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $6.85 | 2,189,781 | $14,999,999.85 | 6,788,609 | 2023-10-16 | Filing | |
| $6.85 | 2,189,781 | $14,999,999.85 | 6,788,609 | 2023-10-16 | Filing | |
| $8.55 | 10,150 | $86,735.81 | 11,259,438 | 2023-10-12 | Filing | |
| $6.85 | 2,189,781 | $14,999,999.85 | 11,249,288 | 2023-10-12 | Filing | |
| $6.43 | 31,557 | $202,845.24 | 9,059,507 | 2023-04-28 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $33.21 | 11,136 | $369,817.65 | 11,136 | 2025-06-23 | Filing | |
| $32.74 | 2,766 | $90,547.22 | 24,070 | 2025-06-23 | Filing | |
| $32.16 | 17,550 | $564,357.11 | 26,836 | 2025-06-23 | Filing | |
| $32.53 | 54 | $1,756.56 | 34,920 | 2025-06-16 | Filing | |
| $31.96 | 2,977 | $95,131.82 | 34,974 | 2025-06-16 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 13,794,490 | $443,492,854 | 0.03% | |
| 2. | 7,307,269 | $234,928,696 | 0% | |
| 3. | 4,845,205 | $155,773,341 | 0% | |
| 4. | 3,134,140 | $100,762,601 | 0% | |
| 5. | 2,661,608 | $85,578,910 | 1.7% |
