| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Newtyn Management Noah Levy And Eugene Dozortsev | 633,297 | $3,109 | +350% | 0.58% |
| 2. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,110,588 | $5,453 | 0.53% | |
| 3. | Rubric Capital Management David Rosen | 476,164 | $2,338 | 0.22% | |
| 4. | Clearline Capital Marc Majzner | 59,331 | $291 | 0.18% | |
| 5. | LMR Partners Ben Levine, Andrew Manuel And Stefan Renold | 42,910 | $211 | 0.01% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $7.20 | 5,000 | Director | 754,448 | 2016-03-17 | Filing | |
| $7.65 | 5,000 | Director | 749,448 | 2016-03-15 | Filing | |
| $7.09 | 10,000 | Director | 744,448 | 2016-03-08 | Filing | |
| $6.27 | 10,000 | Director | 734,448 | 2016-03-03 | Filing | |
| $6.63 | 5,000 | Director | 724,448 | 2016-03-02 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.23 | 7,796 | Director | 22,681 | 2017-09-15 | Filing | |
| $14.20 | 100 | Director | 22,681 | 2017-09-14 | Filing | |
| $14.27 | 6,800 | Director | 22,681 | 2017-09-13 | Filing | |
| $14.46 | 14,756 | Director | 22,681 | 2017-09-11 | Filing | |
| $3.72 | 4,097 | Officer | 101,731 | 2017-05-12 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 34,130 | $182 | 0.06% | |
| 2. | 14,898 | $79 | 0.05% | |
| 3. | 1,400 | $8 | 0% | |
| 4. | 3,055 | $16 | 0% |
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