| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Opaleye Management James A. Silverman | 3,905,000 | $188,142,900 | 26.6% | |
| 2. | Private Capital Management Gregg J. Powers | 1,855,664 | $89,405,892 | -5% | 7.99% |
| 3. | Royce & Associates Chuck Royce | 533,013 | $25,680,566 | -4% | 0.26% |
| 4. | Marshall Wace LLP Paul Marshall And Ian Wace | 508,116 | $24,481,030 | -11% | 0.02% |
| 5. | Braidwell LP Alex Karnal | 342,391 | $16,496,398 | -61% | 0.49% |