| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 11,668,473 | $2,228,678 | +34% | 0.09% |
| 2. | Soleus Capital Guy Levy | 4,362,026 | $833,147 | +93% | 0.04% |
| 3. | LMR Partners Ben Levine, Andrew Manuel And Stefan Renold | 540,984 | $103,328 | +171% | 0% |
| 4. | Two Sigma Advisors John Overdeck And David Siegel | 214,800 | $41,027 | -18% | 0% |
| 5. | Citadel Investment Group Ken Griffin | 144,449 | $27,590 | +168% | 0% |