| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 15,518,492 | $251,709,940 | 5.92% | |
| 2. | RA Capital Management Peter Kolchinsky | 10,428,437 | $169,149,248 | +6% | 2.08% |
| 3. | Baker Bros. Advisors Julian Baker And Felix Baker | 7,305,940 | $118,502,347 | 0.86% | |
| 4. | Braidwell LP Alex Karnal | 5,210,831 | $84,519,679 | 2.51% | |
| 5. | Cormorant Asset Management Bihua Chen | 4,010,000 | $65,042,200 | -6% | 4.49% |