| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 7,000,000 | $21,350,000 | 0.87% | |
| 2. | Redmile Group Jeremy Green | 6,300,644 | $19,216,964 | 1.87% | |
| 3. | Millennium Management Israel Englander | 2,822,823 | $8,609,610 | +13% | 0% |
| 4. | Woodline Partners Michael Rockefeller And Karl Kroeker | 2,638,275 | $8,046,739 | +151% | 0.04% |
| 5. | Opaleye Management James A. Silverman | 2,600,000 | $7,930,000 | 1.12% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $4.19 | 33,000 | $138,270.00 | 33,000 | 2025-12-01 | Filing | |
| $4.47 | 4,115 | $18,394.05 | 50,290 | 2025-12-01 | Filing | |
| $4.28 | 422,613 | $1,808,783.64 | 9,728,637 | 2025-11-21 | Filing | |
| $4.48 | 400,000 | $1,792,000.00 | 9,306,024 | 2025-11-20 | Filing | |
| $3.94 | 500,000 | $1,970,000.00 | 8,906,024 | 2025-11-19 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $2.58 | 1,116 | $2,879.28 | 105,084 | 2025-07-14 | Filing | |
| $2.58 | 1,117 | $2,881.86 | 121,616 | 2025-07-14 | Filing | |
| $2.61 | 853 | $2,226.33 | 130,689 | 2025-07-14 | Filing | |
| $2.96 | 5,521 | $16,342.16 | 33,479 | 2025-02-18 | Filing | |
| $2.97 | 5,515 | $16,379.55 | 83,814 | 2025-02-18 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 11,081,163 | $33,797,548 | 0% | |
| 2. | 7,899,008 | $24,091,974 | 0% | |
| 3. | 5,835,112 | $17,797,091 | 0% | |
| 4. | 5,249,069 | $16,009,660 | 1.06% | |
| 5. | 5,157,290 | $15,729,735 | 0.33% |