| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 451,009 | $10,010 | -5% | 0.75% |
| 2. | Cormorant Asset Management Bihua Chen | 740,621 | $16,438 | 0.65% | |
| 3. | Redmile Group Jeremy Green | 1,164,002 | $25,835 | -1% | 0.61% |
| 4. | Rock Springs Capital Management Kris Jenner, Gordon Bussard, Graham Mcphail | 225,000 | $4,994 | 0.15% | |
| 5. | Alkeon Capital Management Panayotis Takis Sparaggis | 439,594 | $9,756 | -13% | 0.03% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $16.00 | 270,000 | Director | 505,099 | 2019-06-24 | Filing | |
| $16.00 | 270,000 | Large Shareholder | 505,099 | 2019-06-24 | Filing | |
| $16.00 | 250,000 | Director | 250,000 | 2019-06-24 | Filing | |
| $16.00 | 400,000 | Large Shareholder | 4,104,858 | 2019-06-24 | Filing | |
| $16.00 | 900,000 | Large Shareholder, Director | 5,415,203 | 2019-06-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $27.14 | 6 | Large Shareholder | 3,233,671 | 2020-02-12 | Filing | |
| $27.05 | 2,184 | Large Shareholder | 3,233,677 | 2020-02-11 | Filing | |
| $27.08 | 7,836 | Large Shareholder | 3,225,861 | 2020-02-10 | Filing | |
| $27.03 | 6,102 | Large Shareholder | 3,233,697 | 2020-02-06 | Filing | |
| $25.99 | 28,608 | Large Shareholder | 3,239,799 | 2020-02-05 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 3,940,543 | $87,460 | 37.49% | |
| 2. | 891,201 | $19,780 | 0.24% | |
| 3. | 10,409 | $231 | 0.18% | |
| 4. | 19,531 | $433 | 0.07% | |
| 5. | 30,200 | $595 | 0.07% |
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