ProQR Therapeutics N.V. (PRQR): Jennison Associates Grabbed A Large Chunk Of This Biotech Stock

Item 5 Ownership of Five Percent or Less of a Class:

If this statement is being filed to report the fact that as of

the date hereof the reporting person has ceased to be the

beneficial owner of more than five percent of the securities,

check the following ( ).

Item 6 Ownership of More than Five Percent on Behalf of

Another Person:

The securities that are subject to this report are owned by and held for

the Managed Portfolios. Any dividends received from such securities,

or the proceeds of any sale of such securities, are for the benefit of,

and are held for Managed Portfolios.

One such Managed Portfolio, the Prudential Sector Funds, Inc.- Prudential

Health Sciences Fund d.b.a. Prudential Jennison Health Sciences Fund owns

more than 5% of the class of securities which are the subject of this

report.

Item 7 Identification and Classification of the Subsidiary

which Acquired the Security being Reported on by the Parent

Holding Company: Not Applicable

Item 8 Identification and Classification of Members of the

Group: Not Applicable