Perceptive Advisors and Foamix Pharmaceuticals Ltd.

Page 5 of 8 – SEC Filing

Item 1(a).

Name of Issuer:

Foamix Pharmaceuticals Ltd. (the Issuer)

Item 1(b).

Address of Issuers Principal Executive Offices:

2 Holzman Street, Weizmann Science Park, Rehovot, Israel

Item 2(a).

Names of Persons Filing:

The names of the persons filing this report (collectively, the Reporting Persons) are:

Perceptive Advisors LLC (Perceptive Advisors)

Joseph Edelman (Mr. Edelman)

Perceptive Life Sciences Master Fund, Ltd. (the Master Fund)

Item 2(b).

Address of Principal Business Office or, if None, Residence:

The address of the principal business office of each of the Reporting Persons is:

51 Astor Place, 10th Floor

New
York, NY 10003

Item 2(c).

Citizenship:

Perceptive Advisors is a Delaware limited liability company

Mr. Edelman is a United States citizen

The Master Fund is a Cayman Islands corporation

Item 2(d).

Title of Class of Securities:

Ordinary Shares, par value NIS 0.16 per share (Ordinary Shares)

Item 2(e).

CUSIP Number:

M46135105

Item 3.

If this statement is filed pursuant to §§ 240.13d-1(b)
or 240.13d-2(b) or (c), check whether the person filing is a
:

Not
applicable.

Item 4.

Ownership.

The information required by this item with respect to each Reporting Person is set forth in Rows 5 through 9 and 11 of the cover page to this
Schedule 13G. The ownership percentages reported are based on 52,499,324 outstanding Ordinary Shares, as reported in the Issuers prospectus supplement filed on September 14, 2018.

The Master Fund directly holds 3,307,424 Ordinary Shares. Perceptive Advisors serves as the investment manager to the Master Fund and may be
deemed to beneficially own the securities

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