Dear Valued Visitor,

We have noticed that you are using an ad blocker software.

Although advertisements on the web pages may degrade your experience, our business certainly depends on them and we can only keep providing you high-quality research based articles as long as we can display ads on our pages.

To view this article, you can disable your ad blocker and refresh this page or simply login.

We only allow registered users to use ad blockers. You can sign up for free by clicking here or you can login if you are already a member.

Mylan NV (MYL) Partnership Means The Race Is Back On For Mabion SA (MAB) And Its Billion Dollar Rituximab Biosimilar

Polish biotech company Mabion SA (WSE:MAB) just announced the signing of a supply and commercialization agreement with Mylan NV (NASDAQ:MYL), by way of its subsidiary Mylan Ireland, which will see the latter pick up exclusive rights to the former’s biosimilar of Mabthera/Rituximab (Mabion CD20) in all EU countries and non-EU Balkan states.

If you are following EGLT or COLL then you must read our research now! Click here for the full report!

The agreement paves the way for the two companies to commercialize a drug that generated more than $7 billion in global sales for its branded marketer Roche Holding Ltd. (ADR) (OTCMKTS:RHHBY) back in 2013.

Here’s what we know, and what the collaboration might mean for all the parties involved going forward.

First, a bit of history.

trade, deal, investor, background, partnership, money, forex, capital, market, bar, business, night, fingers, diagram, cooperation, finance, data, stock, analysis, bank, report,


The drug in question, Rituximab, first picked up approval from the US Food and Drug Administration (FDA) for treating non-Hodgkin’s lymphoma in 1997, which was followed by European Union (EU) approval in June 1998. It went on to become one of the top, if not the top, selling cancer drugs across the subsequent decade and a half, spearheading Roche’s oncology portfolio and cementing a spot on the World Health Organization’s (WHO) list of essential medicines – a spot it still holds, and that we will return to shortly.

At the end of 2013, however, the drug came out from under patent protection. With a large potential revenue pot for a company that could develop and commercialize a generic version, a number of companies got to work developing an alternative. One of these was Mabion SA (WSE:MAB). Others included Boehringer Ingelheim, Teva Pharmaceutical Industries Ltd (ADR) (NYSE:TEVA) and SAMSUNG ELECTRONIC KRW5000 (OTCMKTS:SSNLF). Each of these latter three mentioned companies have since dropped their development programs, for various reasons, leaving Mabion an opportunity to get in ahead of the wave of big names and bring its product to market in Europe.

Looking at the drug specifically, its an oncology focus in this instance (although there are other applications), as mentioned, and its an IV administration antibody that targets a protein called CD20. This protein primarily resides on the surface of B cells, which are a component of our immune system, and can cause a range of problems if they become overactive or dysfunctional. Rituximab targets the protein, and on identification, induces apoptosis (just another word for a sort of programmed cell death) in the cells that express it – in this instance, the problematic B cells.

It’s important to note here that the fact that this is a biologic plays a big part in the ease with which a company can bring a generic version (for accuracy’s sake, we’re going to refer to this as a biosimilar version from here on out) to market.

Follow Mylan N.v. (NASDAQ:MYL)
Trade (NASDAQ:MYL) Now!

DOWNLOAD FREE REPORT: Warren Buffett's Best Stock Picks

Let Warren Buffett, George Soros, Steve Cohen, and Daniel Loeb WORK FOR YOU.

If you want to beat the low cost index funds by 19 percentage points per year, look no further than our monthly newsletter.In this free report you can find an in-depth analysis of the performance of Warren Buffett's entire historical stock picks. We uncovered Warren Buffett's Best Stock Picks and a way to for Buffett to improve his returns by more than 4 percentage points per year.

Bonus Biotech Stock Pick: You can also find a detailed bonus biotech stock pick that we expect to return more than 50% within 12 months.
Subscribe me to Insider Monkey's Free Daily Newsletter
This is a FREE report from Insider Monkey. Credit Card is NOT required.