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Puma Biotechnology Inc (NASDAQ:PBYI) (Benzinga)
Puma Biotechnology Inc (NASDAQ:PBYI) shares dipped 26.4 percent to $66.95. Puma Biotechnology could face a setback in the launch of its breast cancer drug neratinib, as the European Medicines Agency’s Committee for Medicinal Products for Human Use, or CHMP, relayed a “negative trend vote” after a meeting with the biotech company. Cowen downgraded shares of Puma Biotech from Outperform to Market Perform and reduced the price target from $128 to $68.

Baker Hughes A GE Co (NYSE:BHGE) (Reuters)
(Reuters) – General Electric’s oilfield services company Baker Hughes (BHGE.N) reported fourth-quarter revenue on Wednesday that beat analyst estimates and profit that modestly exceeded forecasts as growing U.S. oil production spurred demand for its products. General Electric (GE.N) and Baker Hughes closed a merger of their oilfield services businesses in July, and Wednesday’s report was the second combined earnings release for the newly formed company. Shares sank nearly 5 percent to $34.05 in morning trading.

RPC, Inc. (NYSE:RES) (The Motley Fool)
What happened: Shares of RPC, Inc. (NYSE:RES) slumped on Wednesday, down 10% as of 10:45 a.m. EST, after the oil and gas services specialist reported fourth-quarter results. So what: RPC posted $427.3 million in revenue during the fourth quarter, which was a jaw-dropping 93.4% above the year-ago quarter.

General Dynamics Corporation (NYSE:GD) (Reuters)
(Reuters) – General Dynamics Corp (GD.N) said on Wednesday the U.S. administration’s lack of appointees at the Pentagon and failure of Congress to pass a federal budget contributed to the aerospace and defense company missing analysts’ sales expectations.

United Continental Holdings Inc (NYSE:UAL) (CNBC)
United Continental Holdings, the parent of United Airlines, posted earnings Tuesday that outpaced analyst estimates. But shares plunged in post-market trading during a long-awaited investor presentation in which the airline unveiled a strategy to add more seats to the market while keeping a lid on costs. Some analysts appeared unconvinced that the plan would help expand margins.