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Market Movers Today: Spectrum Pharmaceuticals, Inc. (SPPI), Autodesk, Inc. (ADSK), H & R Block Inc (HRB), ShiftPixy Inc (PIXY), and More

Spectrum Pharmaceuticals, Inc. (NASDAQ:SPPI) (The Motley Fool)
What happened: Shares of Spectrum Pharmaceuticals, Inc. (NASDAQ:SPPI) are losing ground after the oncology-focused biotech’s fourth-quarter earnings failed to impress on two fronts. The company’s commercial-stage drugs missed sales expectations and a late-stage cancer hopeful’s journey to the Food and Drug Administration could take longer than expected. In response, the stock is down 17.7% as of 12:37 p.m. EST on Tuesday.

Autodesk, Inc. (NASDAQ:ADSK) (MarketWatch)
Shares of Autodesk Inc. ADSK, +13.53% are up 12.5% Wednesday and trading at record-high levels after the software company reported better-than-expected quarterly earnings late Tuesday. Many analysts praised the results, with at least 14 raising their price targets on the stock, according to FactSet. “There has been a lot of concern about the subscription net addition metric since the last quarter call and we believe this quarter’s result and fiscal 2019 guidance will finally focus investors on ARR, the most important metric in the subscription transition just like what we saw with Adobe ADBE, +1.51% ” wrote J.P. Morgan analyst Sterling Auty, who raised his price target to $150 from $130 and has an overweight rating on the stock.

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H & R Block Inc (NYSE:HRB) (CNBC)
H&R Block — Shares of H&R Block rose nearly 5 percent in low-volume premarket trading after the company reported a smaller-than-expected loss for the previous quarter. H&R Block lost $1.16 per share last quarter. Analysts polled by Reuters expected a loss of $1.29 a share. The company said in a release it had a “strong tax season.”

ShiftPixy Inc (NASDAQ:PIXY) (Benzinga)
ShiftPixy Inc shares rose 53.3 percent to $3.94. ShiftPixy disclosed that it is ‘leveraging blockchain as a digital ledger for all human capital transactions.’

Zafgen Inc (NASDAQ:ZFGN) (The Motley Fool)
What happened: Shares of clinical-stage biopharma Zafgen (NASDAQ:ZFGN) rose more than 21% today after the company announced full-year 2017 earnings. As a development-stage company, there weren’t any important financial metrics for investors to pore over aside from the year-end cash and cash equivalents balance, which stood at $102 million. More important for investors was a slew of updates from the pipeline. Zafgen reported positive interim results from an ongoing phase 2 trial for a drug candidate being evaluated as a potential treatment for type 2 diabetes.

Advanced Micro Devices, Inc. (NASDAQ:AMD) (MarketWatch)
Shares of Advanced Micro Devices Inc. AMD, +3.87% surged 5.6% in active midday trade to pace the gainers in the PHLX Semiconductor Index SOX, -0.13% and to buck the sharp selloffs in the chip sector and broader stock market. The chip sector tracker (SOX) fell 0.7% and the S&P 500 SPX, -0.63% shed 0.9%. AMD’s trading volume neared 90 million shares, compared with the full-day average of about 60 million shares, according to FactSet, and enough to make the stock the most actively traded on major U.S. exchanges.

Dollar Tree, Inc. (NASDAQ:DLTR) (Benzinga)
Dollar Tree, Inc. dropped 15.9 percent to $87.81 after the company posted downbeat quarterly earnings and issued a weak forecast.

Ross Stores, Inc. (NASDAQ:ROST) (CNBC)
Ross Stores – The off-price retailer reported quarterly earnings and revenue that beat analysts’ expectations. Same-store sales, a key metric for retailers, rose 5 percent in the previous quarter, surpassing an expected gain of 3.1 percent.

Netflix, Inc. (NASDAQ:NFLX) (Barron’s)
Shares of Netflix (NFLX) are down $3.40, or 1%, at $321.82, after Stifel Nicolaus’s Scott Devitt this morning cut his rating on the stock to Hold from Buy, even though he raises his price target to $325 from $283, writing that the share price “may have sprinted ahead of fundamentals in the short-term.” “Netflix shares are up by nearly +70% YTD (versus the S&P 500 up +2% YTD), following a +55% move in 2017.” The downgrade follows several price target increases the last couple days.