Loxo Oncology Inc. (LOXO): OrbiMed Advisors Reports Percentage of Ownership Change

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Samuel Isaly’s OrbiMed Advisors recently filed a 13D filing with the SEC in which it reported owning 2.18 million common shares of Loxo Oncology Inc. (NASDAQ:LOXO), which account for 10.04% of the company’s outstanding stock. Although the number of shares owned by Orbimed Advisors hasn’t changed, the filing was submitted in order to report a change in the percentage of shares that it owns, due to the amount of outstanding shares increasing. Previously, the 2.18 million shares owned by OrbiMed Advisors amassed 11.12% of the company’s outstanding stock.

Loco Oncology is a biopharmaceutical company that works on discovering various therapeutics to help treat people with genetically defined cancer. One such treatment is LOXO 101, which recently received Breakthrough Therapy Designation from the U.S. Food and Drug Administration. Over the last 12 months, the company’s shares have gained 37.13%. For the second quarter of 2016, the company reported a net loss of $15.92 million amounting to a net loss per share of $0.77, compared to a net loss of $8.06 million or $0.49 per share for the same quarter of the previous year. 

Samuel Isaly Orbimed Advisors

As per Insider Monkey’s hedge fund database of 766 13F-filing hedge funds, at the end of the first quarter of 2016, 14 of those investors were long the stock, down from 18 a quarter earlier. The largest position was reported by Dennis Purcell’s Aisling Capital, worth close to $103.8 million, while the second-biggest stake was held by Orbimed Advisors. Some other smart money managers with similar bullishness included Phill Gross and Robert Atchinson’s Adage Capital Management, Richard Driehaus’ Driehaus Capital, and Zach Schreiber’s Point State Capital.

Among investors who lost interest in Loxo Oncology (NASDAQ:LOXO) and decided to sell their shares during the first quarter were Jacob Gottlieb’s Visium Asset Management, which said goodbye to its position worth about $11.4 million in stock, and Dmitry Balyasny’s Balyasny Asset Management, which sold off a position worth about $0.8 million.

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You can access the original SEC filing by clicking here.

Ownership Summary Table

Name Sole Voting Power Shared Voting Power Sole Dispositive Power Shared Dispositive Power Aggregate Amount Owned Power Percent of Class
OrbiMed Advisors 0 2,175,857 0 2,175,857 2,175,857 10.04%
OrbiMed Capital GP V 0 2,175,857 0 2,175,857 2,175,857 10.04%
Samuel D. Isaly 0 2,175,857 0 2,175,857 2,175,857 10.04%

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Page 1 of 12 – SEC Filing

Washington, D.C. 20549
Under the Securities Exchange Act of 1934
(Amendment No. 2)*


(Name of Issuer)


(Title of Class of Securities)
(CUSIP Number)
OrbiMed Advisors LLC
OrbiMed Capital GP V LLC
Samuel D. Isaly
601 Lexington Avenue, 54th Floor
New York, NY 10022

Telephone:  (212) 739-6400

(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)

August 3, 2016

(Date of Event Which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of § 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box o.
Note:  Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits.  See § 240.13d-7(b) for other parties to whom copies are to be sent.
*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

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