Jim Cramer’s Hottest GLP-1 and Weight Loss Stock Picks

7. Eli Lilly and Company (NYSE:LLY)

Number of Hedge Fund Holdings in Q3 2024: 106

Number of Hedge Fund Holdings in Q4 2025: 137

Performance Since Cramer’s Remarks: 21%

Date/Month of Cramer’s Remarks: January 14th, 2025

Eli Lilly and Company (NYSE:LLY) is the premier player in the weight loss drug industry. Its shares are up by 6% over the past year and by 21% since Cramer discussed them in January 2025. They closed 8% higher on October 1st, on the day it surfaced that the Trump administration would give pharmaceutical giant Pfizer a three-year grace from tariffs. Eli Lilly and Company (NYSE:LLY)’s shares then proceeded to rise by 36% between the end of October and late November. The move let the firm become the first in its sector to cross a trillion-dollar valuation. Throughout 2025, Cramer remained one of Eli Lilly and Company (NYSE:LLY)’s biggest supporters. He continued to wonder whether the firm could touch a trillion-dollar valuation and asserted that apart from weight loss drugs, its portfolio of cardiovascular and other treatments could generate additional tailwinds. While Eli Lilly and Company (NYSE:LLY)’s shares are down by 18% year-to-date, they did close 10% higher on February 4th. The move occurred as the firm reported its fourth-quarter earnings. Here’s what Cramer had said about the weight loss company on Mad Money:

“Of course, it’s not just the botched launch that’s holding Lilly back. Bobby Kennedy, Jr. (Robert Kennedy Jr.), Trump’s nominee for Health and Human Services is universally known as an anti-vaccine proponent. Now that’s true, but you can also think of him as a believer in diet and exercise. He’s not a huge fan of the GLP-1 drugs, but the food industry has made that diet and exercise regimen almost impossible for most people. So why not let those who can’t diet or exercise enough, take the shot?.. Yes, the giant head and shoulders pattern in the stock’s chart… So short-term things may look ugly for Lilly. I’m sorry, I’m a long-term believer. I say that you want to (*buzzer sound* buy, buy, bye).”