Dear Valued Visitor,

We have noticed that you are using an ad blocker software.

Although advertisements on the web pages may degrade your experience, our business certainly depends on them and we can only keep providing you high-quality research based articles as long as we can display ads on our pages.

To view this article, you can disable your ad blocker and refresh this page or simply login.

We only allow registered users to use ad blockers. You can sign up for free by clicking here or you can login if you are already a member.

Foresite Capital Betting It All On These Four Healthcare Stocks

Jim Tananbaum’s Foresite Capital has filed its latest 13F with the Securities and Exchange Commission for the reporting period of March 31, disclosing the long positions held in its equity portfolio, which amounted to a mere four holdings. The San Francisco-based fund, founded by Tananbaum in 2011, invests in both public and private healthcare companies with late-stage products, providing them with valuable venture capital and industry expertise as they seek to have novel treatments approved for use and marketed and sold to the public.

Jim Tananbaum - Foresite Capital

While Foresite Capital has approximately $650 million in total assets under management, the value of its equity portfolio took a sharp drop to just $21.74 million from $67.90 million at the end of 2014, as the fund sold off its positions in Karyopharm Therapeutics Inc (NASDAQ:KPTI) and Xencor Inc (NASDAQ:XNCR), previously its top two positions, which had accounted for nearly 70% of its equity portfolio. We’ll now take a look at the fund’s four remaining positions, beginning with its top holding, Orexigen Therapeutics, Inc. (NASDAQ:OREX). 

Foresite’s position in Orexigen Therapeutics, Inc. (NASDAQ:OREX) was trimmed slightly, by less than 1% to 1.23 million shares valued at $9.63 million. Following the changes to its equity portfolio, Orexigen now accounts for over 44% of its portfolio’s total value, up from just 11%. Orexigen Therapeutics, Inc. (NASDAQ:OREX) has been a big underperformer throughout its lifetime, down by more than 52% since it went public in the middle of 2007. Orexigen, which sells the obesity treatment Contrave, has struggled to find profitability over the years as it suffers from low profit margins and a high debt load. Shares are up 6% this year, though they were up nearly 40% at one point in early March after a brief spike. David Lamond’s Lamond Capital Partners liked Orexigen at its reduced fourth quarter price, opening a new position of 1.89 million shares during the quarter. Orexigen hit a two-year low in early October and has rebounded to gain 87% since then.

BioDelivery Sciences International Inc. (NASDAQ:BDSI) ranks second in Foresite’s portfolio and also stands as one of Julian Robertson’s top long-term stock picks. Foresite’s position was decreased by 26% down to 494,468 shares with a value of $5.19 million. BioDelivery Sciences International Inc. (NASDAQ:BDSI) was enjoying a strong run through early 2015, up by 27% at one point in early March before disappointing results from a Phase 3 trial for its Clonidine topical gel were released. The treatment, a pain reliever for those suffering from diabetic neuropathy, failed to outperform a placebo for pain relief, which was a surprise and disappointment given the previously strong trial results. BioDelivery Sciences International Inc. (NASDAQ:BDSI) is not giving up on the treatment however, and has two other treatments, Bunavail and Belbuca, the latter of which has been approved by the FDA for the treatment of opioid addiction.

DOWNLOAD FREE REPORT: Warren Buffett's Best Stock Picks

Let Warren Buffett, George Soros, Steve Cohen, and Daniel Loeb WORK FOR YOU.

If you want to beat the low cost index funds by 19 percentage points per year, look no further than our monthly newsletter.In this free report you can find an in-depth analysis of the performance of Warren Buffett's entire historical stock picks. We uncovered Warren Buffett's Best Stock Picks and a way to for Buffett to improve his returns by more than 4 percentage points per year.

Bonus Biotech Stock Pick: You can also find a detailed bonus biotech stock pick that we expect to return more than 50% within 12 months.
Subscribe me to Insider Monkey's Free Daily Newsletter
This is a FREE report from Insider Monkey. Credit Card is NOT required.