In this article, we will list the 5 Most Active Penny Stocks to Buy. Please visit 10 Most Active Penny Stocks to Buy if you’d like to see an extended list and how we came up with the list of most active penny stocks to buy.
5. Nuvation Bio Inc. (NYSE:NUVB)
Nuvation Bio Inc. (NYSE:NUVB) is one of the 10 most active penny stocks to buy.
As of March 16, 2026, Wall Street remains optimistic about Nuvation Bio Inc. (NYSE:NUVB).
With over 90% of analysts covering Nuvation Bio Inc. (NYSE:NUVB) maintaining bullish ratings, the consensus price target is $12.00, indicating a potential upside of 166.67%.
As investors focus on IBTROZI’s commercial launch and the company’s growing oncology pipeline, sentiment remains positive. Moreover, analyst confidence has been bolstered by Nuvation Bio Inc. (NYSE:NUVB)’s early commercialization progress.
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Consequently, RBC Capital analysts increased the firm’s price target from $12.00 to $13.00 and reaffirmed their “Outperform” rating for Nuvation Bio Inc. (NYSE:NUVB) on March 3, 2026. They highlighted the long-term potential across the company’s oncology pipeline and the strong physician adoption of IBTROZI.
According to Nuvation Bio Inc.’s (NYSE:NUVB) March 2, 2026, fourth-quarter earnings release, IBTROZI generated $15.70 million in net product revenue in Q4, with 216 new patients starting treatment. A $25.00 million milestone payment from Nippon Kayaku was the main driver of the company’s $26.20 million collaboration and license revenue, helping its cash and equivalents reach $529.20 million as of December 31, 2025. Nuvation Bio reported a net loss of $36.6 million, or $(0.11) per share. The net loss for the comparable period in 2024 was $49.4 million, or $0.15 per share.
Nuvation Bio Inc. (NYSE:NUVB) is a biopharmaceutical company developing new treatments for difficult-to-treat cancers. The company was founded by David Hung in 2018, and its headquarters are in New York City.
4. Gossamer Bio, Inc. (NASDAQ:GOSS)
Gossamer Bio, Inc. (NASDAQ:GOSS) is included in our list of the 10 most active penny stocks to buy.
As of March 16, 2026, Gossamer Bio, Inc. (NASDAQ:GOSS) has support from 44% of analysts who maintain a “Buy” rating for the stock. The consensus price target of $1.00 indicates an upside potential of 117.39%.
Amid an uncertain regulatory environment, analysts recently revised their forecasts for Gossamer Bio, Inc. (NASDAQ:GOSS)’s primary therapy, seralutinib. This therapy is being developed for pulmonary arterial hypertension (PAH).
H.C. Wainwright & Co. maintained a “Buy” rating but lowered its price target for Gossamer Bio, Inc. (NASDAQ:GOSS) from $10 to $5 on March 6, 2026. A more cautious outlook on the program’s development prospects led the firm to lower its probability of success for seralutinib in PAH from 70% to 50%.
Additionally, on March 5, 2026, Oppenheimer & Co. reiterated its “Outperform” rating while lowering its price target from $12 to $3. While citing short-term regulatory uncertainties, the firm pointed out that a June FDA interaction, Week 48 results, and future CT FRI substudy data might help reduce risk in seralutinib’s approval pathway and potentially lead to a re-rating in the shares.
Gossamer Bio, Inc. (NASDAQ:GOSS) is a clinical-stage biopharmaceutical company developing treatments for immunology, inflammation, and oncology, notably GB001 for eosinophilic asthma. Established in 2015, it is based in San Diego, California.
3. UWM Holdings Corporation (NYSE:UWMC)
UWM Holdings Corporation (NYSE:UWMC) is one of the 10 most active penny stocks to buy.
As of March 16, 2026, Wall Street sentiment toward UWM Holdings Corporation (NYSE:UWMC) remains divided. The consensus price target of $6 indicates an upside of 63.93%, with more than 65% of analysts covering the company maintaining a “Hold” rating. The stock has dropped more than 16% in 2026 so far.
On March 9, 2026, UWM Holdings Corporation (NYSE:UWMC) revised its financial outlook in response to uncertainty in the mortgage market. With this revision, management aims to provide investors with a more thorough understanding of the company’s strategic direction and short-term performance.
Before Two Harbors Investment Corp.’s shareholder meeting on March 9, 2026, UWM Holdings Corporation (NYSE:UWMC) updated its guidance. According to CEO Mat Ishbia, even if the proposed acquisition of Two Harbors fails to close, management projects total revenue of $800 million to $900 million in Q1 2026 and $3.5 billion to $4.5 billion in full-year 2026.
UWM Holdings Corporation (NYSE:UWMC)’s loan origination volume in Q4 2025 reached $49.6 billion, its highest quarterly level since 2021, indicating strong operational momentum.
By 2026, UWM Holdings Corporation (NYSE:UWMC) expects its AI voice assistant “Mia” to handle more than 12 million calls, improving efficiency and enabling the company to handle two to three times its current loan volume without adding more employees.
UWM Holdings Corporation (NYSE:UWMC) is a wholesale mortgage lender that provides independent brokers and financial institutions with technology-driven tools for residential loan origination. It is headquartered in Pontiac, Michigan, and was established in 1986.
2. Peloton Interactive, Inc. (NASDAQ:PTON)
Peloton Interactive, Inc. (NASDAQ:PTON) is included in our list of the 10 most active penny stocks to buy.
On March 16, 2026, Peloton Interactive, Inc. (NASDAQ:PTON) made a strategic move away from its typical focus on at-home connected fitness, unveiling the Peloton Commercial Series, its first bike and treadmill designed for busy gym floors. The launch demonstrates Peloton’s broader goal of expanding across the global fitness and wellness ecosystem.
To address the multibillion-dollar commercial fitness market, Peloton Interactive, Inc. (NASDAQ:PTON)’s Commercial Business Unit (CBU) developed these products for the segment.
This unit was founded in 2025 by integrating Precor and Peloton for Business. According to CEO Peter Stern, the move represents Peloton’s entry into the gym industry. He noted that the company aims to close the fitness gap between home and gym by combining its digital platform and training programs with robust commercial-grade equipment.
Peloton Interactive, Inc. (NASDAQ:PTON)’s software ecosystem and Precor’s industrial-grade architecture will be combined to create the first connected bike and treadmill in the Commercial Series. The CBU recorded 10% year-over-year revenue growth in fiscal Q2, and Peloton may expand internationally due to Precor’s presence in more than 60 countries.
Shipments to the United States, United Kingdom, Canada, Germany, Australia, and Austria are anticipated in late 2026, and the products will make their debut at the Health & Fitness Association Show.
Peloton Interactive, Inc. (NASDAQ:PTON) offers streaming instructor-led exercise classes and connected fitness equipment through product sales and subscriptions. The company was established in 2012 and is headquartered in New York City.
1. Snap Inc. (NYSE:SNAP)
Snap Inc. (NYSE:SNAP) is included in our list of 10 most active penny stocks to buy.
On March 13, 2026, Snap Inc. (NYSE:SNAP) shares fell to a 52-week low of $4.52. This reflects growing investor concerns about the company as it navigates a challenging market environment.
The stock has declined by more than 46.35% in the last year and 42.57% year-to-date, suggesting that advertising demand remains weak.
Despite these challenges, analysts remain cautious about Snap Inc.’s (NYSE:SNAP) potential.
Brian Nowak, an analyst at Morgan Stanley, lowered his price target for Snap Inc. (NYSE:SNAP) from $9.50 to $6.50 on February 23, 2026. He kept the stock’s “Equal Weight” rating.
The analyst noted that Snap Inc. (NYSE:SNAP)’s primary business is performing better than expected. He also emphasized the need for clarity regarding when the company will make about $400 million in high-margin income from its deal with Perplexity, which remains in the negotiation stage.
Furthermore, Morgan Stanley noted that Snap Inc. (NYSE:SNAP)’s performance remains below that of the broader digital advertising industry.
Separately, Citigroup reduced its price target for Snap Inc. (NYSE:SNAP) from $10 to $6 in mid-February 2026, while maintaining a “Neutral” rating in response to the company’s Q4 results. The target adjustment was driven by ongoing headwinds in brand advertising.
Snap Inc. (NYSE:SNAP), a technology company founded in 2010 by Evan Spiegel and Robert C. Murphy, operates Snapchat, a visual messaging platform headquartered in Santa Monica, California.
While we acknowledge the potential of SNAP to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than SNAP and that has 100x upside potential, check out our report about the cheapest AI stock.
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