15 Set-It-and-Forget-It Stocks to Buy in 2026

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11. Exelixis, Inc. (NASDAQ:EXEL)

Number of Hedge Fund Holders: 42

Exelixis, Inc. (NASDAQ:EXEL) is one of the 15 set-it-and-forget-it stocks to buy in 2026.

On March 2, 2026, Exelixis, Inc. (NASDAQ:EXEL) saw its price target from RBC Capital lowered from $46 to $43. The firm’s Sector Perform rating was maintained on the stock. In a research note, RBC Capital pointed out that after the reporting of the data from the HIF-2alpha inhibitors study by Exelixis, Inc. (NASDAQ:EXEL)’s competitor Merck (MRK), the share value of the company will potentially witness a decline in the range of 5% to 10%, owing to competitive pressures.

Separately, H.C. Wainwright raised its price target on Exelixis, Inc. (NASDAQ:EXEL) from $52 to $54 while maintaining a Buy rating on February 12, 2026. Analysts updated their model following the reporting of the results for the fourth quarter of 2025.

As of March 25, 2026, Exelixis, Inc. (NASDAQ:EXEL) maintains a Buy rating from 45% of 22 analysts followed by CNN, with a 1-year average upside potential of 15.47%.

Founded in 1994, Exelixis, Inc. (NASDAQ:EXEL) is a leading oncology-focused biotechnology company with headquarters in California. The company specializes in discovering and commercializing next-generation medicines like CABOMETYX to treat difficult-to-treat cancers.

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