13D Filing: Baker Bros. Advisors and Beigene Ltd (ADR) (BGNE)

Page 2 of 9 – SEC Filing

CUSIP No.    07725L102 Page   2   of   9   Pages

1.

NAMES OF REPORTING PERSONS

Baker Bros. Advisors LP

2.

CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*

(a)  ¨

(b)  ¨

3.

SEC USE ONLY

4.

SOURCE OF FUNDS*

OO

5.

CHECK BOX
IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) or 2(e)       
o

6.

CITIZENSHIP OR PLACE OF ORGANIZATION

Delaware

NUMBER OF
SHARES
BENEFICIALLY
OWNED BY EACH
REPORTING
PERSON WITH

7.

SOLE VOTING POWER: 130,374,760 (1)

8.

SHARED VOTING POWER: 0

9.

SOLE DISPOSITIVE POWER: 130,374,760 (1)

10.

SHARED DISPOSITIVE POWER: 0

11.

AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON: 130,374,760
(1)

12.

CHECK BOX
IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES*        
o

13.

PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

23.6% (2)

14.

TYPE OF REPORTING PERSON*

IA, PN

(1) Includes 50,040,003 of the Ordinary Shares reported
as beneficially owned that are beneficially owned through American Depositary Shares. Each American Depositary Share represents
13 Ordinary Shares of the Issuer.

(2) Based on 552,247,349 Ordinary Shares that will be
outstanding following the offering according to information received from the Issuer on August 12, 2017.

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