12 Best American Penny Stocks to Buy Right Now

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5. Taysha Gene Therapies, Inc. (NASDAQ:TSHA)

Share Price: $3.92

Number of Hedge Fund Holders: 34

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) is one of the best American penny stocks to buy right now. On November 5, Citizens increased its price target on Taysha Gene Therapies, Inc. (NASDAQ:TSHA) from $6 to $8 and kept a Market Outperform rating.

Citizens noted the finalization of the company’s REVEAL pivotal trial for Rett syndrome treatment. The research firm said that the protocol is “the best approach in Rett,” giving Taysha Gene Therapies, Inc. (NASDAQ:TSHA) a huge competitive advantage.

According to Citizens’ analysis, the company has finalized its pivotal protocol and statistical analysis plan. Taysha Gene Therapies, Inc. (NASDAQ:TSHA) now plans to start the trial in Q4 2025. The company has followed new draft guidelines from the FDA.

Citizens noted that continuity in communication with the FDA despite changes in agency leadership should help reduce regulatory risks for Taysha Gene Therapies, Inc.’s (NASDAQ:TSHA) development program. The research firm raised its probability of success estimate for the company’s Rett Syndrome program from 33% to 55%.

Taysha Gene Therapies, Inc. (NASDAQ:TSHA) is a clinical-stage biotechnology company. It focuses on developing adeno-associated virus (AAV)-based gene therapies to treat serious monogenic diseases of the central nervous system.

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