10 Most Commonly Used Illegal Drugs in America

Below we listed the 10 most commonly used illegal drugs in the United States. For a detailed discussion, data source, and more comprehensive list please see this article.

10. Acetyl fentanyl

Number of drug reports: 12190

Percent of all cases: 0.80%

Acetyl fentanyl was most common in the Northeast (5086 reports).

9. Hydrocodone

Number of drug reports: 12747

Percent of all cases: 0.84%

Hydrocodone was most common in the South (7120 reports).

8. Buprenorphine

Number of drug reports: 20552

Percent of all cases: 1.35%

Buprenorphine was most common in the South (9228 reports).

7. Oxycodone

Number of drug reports: 22470

Percent of all cases: 1.48%

Oxycodone was most common in the South (10526 reports).

6. Alprazolam

Number of drug reports: 26635

Percent of all cases: 1.75%

Alprazolam was most common in the South (13191 reports). On the next page we start listing the top 5 most commonly used illegal drugs in the United States.

5. Fentanyl

Number of drug reports: 98954

Percent of all cases: 6.50%

Fentanyl was most common in the Midwest (28556 reports).

4. Heroin

Number of drug reports: 127641

Percent of all cases: 8.39%

Heroin was most common in the Northeast (33678 reports).

3. Cocaine

Number of drug reports: 209086

Percent of all cases: 13.74%

Cocaine was most common in the South (87581 reports).

2. Cannabis/THC

Number of drug reports: 282679

Percent of all cases: 18.58%

Cannabis/THC was most common in the South (121557 reports).

1. Methamphetamine

Number of drug reports: 417867

Percent of all cases: 27.47%

Methamphetamine was most common in the South (183427 reports).

See also top 10 drug free countries in the world, 17 most drug addicted countries in the world and top 20 drug infested cities in America.