10 Best Biotech Stocks with Highest Upside Potential

7. Denali Therapeutics Inc. (NASDAQ:DNLI)

Denali Therapeutics Inc. (NASDAQ:DNLI) is one of the 10 best biotech stocks with highest upside potential.

On April 6, Denali Therapeutics Inc. (NASDAQ:DNLI) revealed that it has received notice from Takeda (NYSE: TAK) about the termination of the collaboration agreement on developing and commercializing DNL593. This move was due to some strategic reasons and is unrelated to the results on the efficacy or safety of the drug.

DNL593 is a progranulin replacement therapy that involves the use of Denali’s Protein Transport Vehicle technology to deliver progranulin to the brain to treat frontotemporal dementia-granulin. Denali has been responsible for all the developmental activities and is going to resume full control over DNL593 and the intellectual property portfolio.

As pointed out by Chief Executive Officer Ryan Watts, although the collaboration was important, full ownership of DNL593 is good news. The firm is still certain that the scientific principle and the evidence collected so far are strong. According to the plan, Denali will present the findings from its phase I/II clinical trials by the end of 2026.

As the first approved means of transporting through the blood-brain barrier, the TransportVehicle technology offers great possibilities for all forms of neurodegeneration, such as frontotemporal dementia.

Denali Therapeutics Inc. (NASDAQ:DNLI) is a biotechnology company that utilizes proprietary technology to address neurodegenerative diseases. Through their TransportVehicle™ platform, and by leveraging the power of biotherapeutics, they develop medicines for some very serious conditions, including lysosomal storage.