| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1.) | Palo Alto Investors William Leland Edwards |
784,719 | $48,857 |  |
5.78% |
| 2.) | Sectoral Asset Management J�R�Me Pfund And Michael Sj�Str�M |
2,146,264 | $133,626 | |
4.1% |
| 3.) | Lmr Partners Ben Levine, Andrew Manuel And Stefan Renold |
312,042 | $19,428 |  |
3.48% |
| 4.) | Zweig Dimenna Partners Joe Dimenna |
667,114 | $41,535 | |
1.86% |
| 5.) | Orbimed Advisors Samuel Isaly |
1,139,500 | $70,945 | |
1.64% |
| 6.) | 13,500,000 | $41,875 | |
1.57% | |
| 7.) | 22,898,000 | $70,834 | |
1.41% | |
| 8.) | Blue Ridge Capital John Griffin |
1,750,000 | $108,955 | |
1.36% |
| 9.) | Baker Bros. Advisors Julian Baker And Felix Baker |
783,311 | $48,769 | +200% |
0.97% |
| 10.) | Mckinley Capital Management Robert B. Gillam |
259,190 | $16,137 | |
0.74% |
| 11.) | Driehaus Capital Richard Driehaus |
169,713 | $10,566 | |
0.44% |
| 12.) | Sac Capital Advisors Steven Cohen |
1,491,591 | $92,866 | |
0.44% |
| 13.) | Bennett Lawrence Management Van Schreiber |
38,850 | $2,419 | |
0.43% |
| 14.) | Balyasny Asset Management Dmitry Balyasny |
461,750 | $28,749 | +1300% |
0.43% |
| 15.) | Polar Capital Brian Ashford-Russell And Tim Woolley |
138,000 | $8,592 | |
0.35% |
| 16.) | 4,040,000 | $12,476 | |
0.24% | |
| 17.) | Columbus Circle Investors Donald Chiboucis |
461,095 | $28,708 | |
0.21% |
| 18.) | Citadel Investment Group Ken Griffin |
1,197,110 | $74,532 | |
0.11% |
| 19.) | Millennium Management Israel Englander |
355,335 | $22,123 | |
0.09% |
| 20.) | D E Shaw D. E. Shaw |
258,397 | $16,088 | +1800% |
0.03% |
| Insider | Price | Amount | Relationship | Remaning Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $21.76 | 161 | Officer | 100,574 | 2012-10-31 | Filing | |
| $21.76 | 548 | Officer | 15,294 | 2012-10-31 | Filing | |
| $27.91 | 588 | Officer | 23,245 | 2012-10-31 | Filing | |
| $13.26 | 333 | Officer | 83,493 | 2011-10-31 | Filing | |
| $13.23 | 201 | Officer | 46,679 | 2011-10-31 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $58.32 | 1,098 | Officer | 43,266 | 2013-06-03 | Filing | |
| $58.34 | 493 | Officer | 14,880 | 2013-06-03 | Filing | |
| $67.16 | 8,710 | Officer | 44,364 | 2013-05-23 | Filing | |
| $65.66 | 11,899 | Officer | 53,074 | 2013-05-22 | Filing | |
| $67.12 | 3,103 | Officer | 20,277 | 2013-05-22 | Filing |
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