Whole Foods Market (WFM), Chipotle Mexican Grill, Inc. (CMG): The 9 Most Obese Countries in the World

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But, it isn’t just grocers that are making the difference. Fresh-Mex chain Chipotle Mexican Grill, Inc. (NYSE:CMG) offers a full line of meats that are free of antibiotics and synthetic hormones under its Food with Integrity pledge. It’s another way of supporting local farmers and a big move toward encouraging healthier eating habits among its consumers.

The reactive response
Understandably, proper diet and exercise will not work for everyone. You can blame it on genetics if you’d like, but the reactive response is where medication approved by the Food and Drug Administration steps in.

Over the past year, we’ve had two new potential chronic weight management drugs approved by the FDA: Qsymia by VIVUS, Inc. (NASDAQ:VVUS) and Belviq by Arena Pharmaceuticals, Inc. (NASDAQ:ARNA). Keep in mind that these aren’t wonder drugs, but they did show significant promise in trials. Belviq, for example, induced weight-loss in excess of 5% in 38% of patients during trials while also providing better glycemic balance in patients with type 2 diabetes. VIVUS, Inc. (NASDAQ:VVUS)’s Qsymia delivered comparatively intriguing results with 62% of recommended dosage patients losing at least 5% of their body weight in trials.

Unfortunately, chronic weight management drugs aren’t magic pills. Qsymia has quite a few restrictions attached to it, including recommendations by the FDA not to use it if you’re pregnant or if you’ve had a recent history of unstable heart disease. Similarly, Belviq isn’t recommended for those who are pregnant and should be closely monitored in patients with congestive heart failure. These concerns were enough to keep Qsymia (known as Qsiva in Europe) and Belviq from being approved by the European Medicines Agency (essentially the FDA of the EU) because of unique safety concerns attached with each drug.

However, there still exists plenty of promise within the U.S. and abroad for both drugs — if they can harness that potential, that is! Arena Pharmaceuticals, Inc. (NASDAQ:ARNA), I’ve long thought, has a one-up on VIVUS in that it’s chosen to partner with pharmaceutical giant Eisai Pharmaceuticals to handle its marketing and distribution, whereas VIVUS is going it alone. Eisai’s experience could be the factor that makes Belviq the better selling anti-obesity drug.

Arena and Eisai’s collaborative deal covers most of North and South America, including the U.S., Mexico, and Canada — the first, second, and sixth most-obese nations — according to the OECD. Arena also has a marketing and distribution partnership in place in South Korea with Ildong Pharmaceuticals. However, South Korea is the least obese country of all, coming in at just 3.8% of the population, so that partnership is far less important than its tie-ins with Eisai.

Another name worth keeping an eye on here is Orexigen Therapeutics, Inc. (NASDAQ:OREX), which is in the process of developing its own chronic weight management drug known as Contrave. The drug was rejected in 2011 because of long-term cardiovascular concerns, but Orexigen Therapeutics, Inc. (NASDAQ:OREX) has run extended safety trials and could resubmit its new drug application before the year is out.

The battle against obesity rages on
With Qsymia only recently becoming available in the U.S. and with Belviq still awaiting final labeling from the U.S. Drug Enforcement Agency before it can find its way onto pharmacy shelves, the reactive side of the business really hasn’t had much chance to shine. Hopefully, within the next three to five years we’ll see the start of a decline in nationwide obesity trends among these nine most-obese countries; but it’ll also take a conscientious effort by the people living there to lead healthier lives. I do feel there’s ample hope down the road for a slimmer global population and plenty of potential for fatter stock prices for some of the companies mentioned here.

The article The 9 Most Obese Countries in the World originally appeared on Fool.com.

Fool contributor Sean Williams has no material interest in any companies mentioned in this article. You can follow him on CAPS under the screen name TMFUltraLong, track every pick he makes under the screen name TrackUltraLong, and check him out on Twitter, where he goes by the handle @TMFUltraLong.The Motley Fool owns shares of, and recommends, Chipotle Mexican Grill and Whole Foods Market.

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