Pfizer Inc. (PFE), Trius Therapeutics, Inc. (TSRX), Forest Laboratories, Inc. (FRX): Gains In This Biotech Could Soon Become Infectious to Investors

Page 1 of 2

The biotech sector can occasionally throw a curveball at investors. For Trius Therapeutics, Inc. (NASDAQ:TSRX) shareholders, they were staring at a meaty fastball right down the heart of the plate yesterday morning.

Pfizer Inc. (NYSE:PFE)Tedizolid mops the floor with its competition
Trius reported its late-stage results from its Establish 2 trial yesterday for Tedizolid — its acute bacterial skin and skin structure infection, or ABSSSI, drug, which is also designed to treat methicillin-resistant staphylococcus aureus, or MRSA. MRSA is a highly infectious bacterial infection often contracted in hospitals, but also relatively treatable if caught early.

The results from Establish 2 only further established Tedizolid as a superior treatment for ABSSSI. Just as we saw in early and mid-stage trials, Tedizolid requires less dosing frequency and packed a bigger efficacy punch than Pfizer Inc. (NYSE:PFE)‘s Zyvox, which has been the kingpin of ABSSSI treatments up until now.

According to Trius Therapeutics, Inc. (NASDAQ:TSRX)’s press release, Tedizolid met the primary endpoint of a greater than 20% decrease in lesion area size in a 48-hour to 72-hour period in 85.2% of instances compared with just 82.6% for Zyvox. Keep in mind, though, that the Tedizolid results were achieved after six days of treatment instead of the 10 days of treatment needed for Zyvox. Tedizolid met its secondary endpoints as well, including a sustained clinical response and an investigator assessment at the end of the therapy (usually seven to 14 days later). Even the adverse event profile of Tedizolid dipped compared to Zyvox, just 20.5% versus 24.8%. All evidence is now pointing to Trius filing for a new drug application in the U.S. and in Europe sometime in the second half of 2013.

Plenty of sales for Trius
An FDA approval of Tedizolid could have a number of implications. For one, it completely mopped the floor with Zyvox in trials, which could make Pfizer Inc. (NYSE:PFE)’s ABSSSI drug nearly obsolete, assuming it gains approval in both the U.S. and E.U. Considering that Zyvox brought in $349 million last year worldwide, Trius Therapeutics, Inc. (NASDAQ:TSRX) could quickly see sales soar beyond $200 million within the first year.

Page 1 of 2
blog comments powered by Disqus
Insider Monkey Headlines
Insider Monkey Small Cap Strategy
Insider Monkey Small Cap Strategy

Insider Monkey beat the market by 52 percentage points in 24 months Click to see monthly returns in table format!

Lists

10 Most Influential Papers In Economics

Top 8 Biggest Charities in the US

10 Worst Celebrity Career Moves Ever

Top 10 Best Paid Tennis Stars in the World

10 Cities with High Demand for Nurses

6 of the Worst Greeting Card Messages Ever Crafted

6 Ways to Make Money in ArcheAge and Build Your Empire

10 Foods To Eat To Lower Cholesterol Levels

The 10 Most Hated Television Characters of All Time

The 30 Worst Halloween Costume Ideas Ever Brought to Horrible Life

10 Vocational Skills in Demand Today with Jobs Waiting to be Filled

10 Best Places to Visit in Central and South America

The 10 Greatest Empires in History Which Nearly Conquered the World

The 6 Cheapest Boarding Schools In America 2015

5 Clear Reasons LoL is Better than DotA, Continues to Rule MOBAs

The Only 9 Teams with a Chance to Win the Super Bowl

The 15 Most Common Phobias in America that Induce Fits of Panic

Top 6 Least Expensive Tourist Destinations in 2014

Jim Goetz, Peter Fenton, Jim Breyer: Top 6 Venture Investors for 2014

Top 15 Billionaires in 2014

5 Pitfalls To Avoid When Buying a Franchise

Top 20 Medical Schools in the US – 2014 Rankings

4 Business Strategies that Turned Jamie Oliver into the World’s Richest Chef

6 Qualities That Make You A Good Team Player

10 High Paying Seasonal Jobs in America this Holiday Season

The 10 Busiest Shipping Lanes in the World

5 Most Valuable Brands in China

The 10 States with Highest Substance Abuse Rates Crippling Their Populace

The Top 10 Things to Do Before You Die That Will Echo for Eternity

The 10 Best Selling Items on Etsy

Top 10 Things to Do in Tokyo, the Greatest City in the World

10 Mistakes on Social Media that Can Harm You and Will Probably Get You Canned

The 10 Best Cities to Find Jobs in 2014

The 10 Most Controversial Songs Of All Time to Hit (and get Banned from) the Airwaves

The 20 Biggest IPOs in US History

The 10 Best Places to Visit in Mexico that Are Beautiful and Safe

7 Bad Habits that Age You Beyond Your Years

The 40 Best Fortune Cookie Sayings That Will Leave You Bemused, Befuddled, or Beguiled

10 Foods to Eat Before a Workout to Make Every Drop of Sweat Count

The 5 Best Documentaries On Netflix You Must See

The Most Heartwarming and Inspirational Story Of This Halloween Season, It Will Make You Cry and Jump For Joy

10 Best Party Songs of All Time to Bring the House Down With

5 New World Order Conspiracy Theories that Will Strangle the World

The 10 Highest Rated Movies of 2014

The 10 Largest Container Shipping Companies in the World

The 10 Largest Armies in the World: Who Should We Be Afraid Of?

Best Warren Buffett Quotes on Money You Need to Hear

The 10 Highest Suicide Rates by Profession

The 20 Most Underrated Movies of All Time

The 10 Fastest Growing Companies in America

Subscribe

Enter your email:

Delivered by FeedBurner

X

Thanks! An email with instructions is sent to !

Your email already exists in our database. Click here to go to your subscriptions

Insider Monkey returned 47.6% in its first year! Wondering How?

Download a complete edition of our newsletter for free!