| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,141,701 | $982,312,581 | +9% | 7.1% |
| 2. | Paulson & Co John Paulson | 1,907,523 | $874,904,499 | -9% | 29.46% |
| 3. | VenBio Select Advisor Kurt Von Emster | 1,833,000 | $840,723,780 | -3% | 10.87% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 265,154 | $121,615,534 | +18% | 0.59% |
| 5. | Hood River Capital Management David Swank | 242,808 | $111,366,317 | -1% | 1.31% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $392.24 | 9,362 | $3,672,178.03 | 1,947,968 | 2025-08-20 | Filing | |
| $392.24 | 862 | $338,113.38 | 202,813 | 2025-08-20 | Filing | |
| $389.89 | 2,506 | $977,058.83 | 1,938,606 | 2025-08-20 | Filing | |
| $389.89 | 231 | $90,064.08 | 201,951 | 2025-08-20 | Filing | |
| $389.00 | 366 | $142,374.00 | 1,936,100 | 2025-08-20 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $575.34 | 2,400 | $1,380,816.00 | 150,074 | 2025-12-04 | Filing | |
| $596.19 | 80 | $47,694.80 | 10,440 | 2025-12-02 | Filing | |
| $595.20 | 74 | $44,045.15 | 10,520 | 2025-12-02 | Filing | |
| $590.37 | 160 | $94,459.60 | 10,594 | 2025-12-02 | Filing | |
| $589.65 | 160 | $94,343.66 | 10,754 | 2025-12-02 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 1,993,687 | $914,424,479 | 11.27% | |
| 2. | 1,842,690 | $845,277,273 | 0.39% | |
| 3. | 1,812,054 | $831,116,688 | 0.01% | |
| 4. | 1,559,712 | $715,377,705 | 0.01% | |
| 5. | 658,097 | $301,842,770 | 0.01% |
Hedge Fund Resource Center 
