| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Baker Bros. Advisors Julian Baker And Felix Baker | 2,141,701 | $982,312,581 | +9% | 7.1% |
| 2. | Paulson & Co John Paulson | 1,907,523 | $874,904,499 | -9% | 29.46% |
| 3. | VenBio Select Advisor Kurt Von Emster | 1,833,000 | $840,723,780 | -3% | 10.87% |
| 4. | Polar Capital Brian Ashford-Russell And Tim Woolley | 265,154 | $121,615,534 | +18% | 0.59% |
| 5. | Hood River Capital Management David Swank | 242,808 | $111,366,317 | -1% | 1.31% |