| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | OrbiMed Advisors Samuel Isaly | 7,959,538 | $312,013,890 | 6.18% | |
| 2. | Polar Capital Brian Ashford-Russell And Tim Woolley | 5,065,933 | $198,584,574 | +45% | 0.71% |
| 3. | Commodore Capital Egen Atkinson And Michael Kramarz | 3,275,000 | $128,380,000 | -31% | 7.43% |
| 4. | Vestal Point Capital Ryan Wilder | 3,250,000 | $127,400,000 | -16% | 3.56% |
| 5. | Citadel Investment Group Ken Griffin | 1,743,915 | $68,361,468 | +23% | 0.01% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $22.07 | 622 | $13,723.27 | 718,749 | 2023-02-23 | Filing | |
| $5.11 | 23,565 | $120,487.85 | 2,872,513 | 2023-02-22 | Filing | |
| $5.25 | 8,194 | $43,010.31 | 2,848,948 | 2023-02-21 | Filing | |
| $4.00 | 629,297 | $2,516,055.27 | 3,880,021 | 2023-01-03 | Filing | |
| $3.93 | 19,299 | $75,845.07 | 3,250,724 | 2022-12-09 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $48.06 | 2,441 | $117,303.48 | 25,000 | 2026-04-17 | Filing | |
| $47.39 | 2,419 | $114,635.44 | 27,441 | 2026-04-17 | Filing | |
| $45.81 | 140 | $6,413.50 | 29,860 | 2026-04-17 | Filing | |
| $35.10 | 40,000 | $1,404,024.00 | 25,000 | 2026-03-25 | Filing | |
| $27.76 | 5,000 | $138,800.00 | 25,000 | 2026-03-17 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 6,829,246 | $267,706,443 | 0.01% | |
| 2. | 3,684,707 | $144,440,514 | 0% | |
| 3. | 2,320,867 | $90,977,986 | 2.17% | |
| 4. | 2,168,162 | $84,991,950 | 0% | |
| 5. | 1,855,644 | $72,741,245 | 5.25% |
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