| No. | Hedge Fund | Shares | Value (x$1000) | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Aquilo Capital Management Marc Schneidman | 1,237,379 | $22,731 | +102% | 8.85% |
| 2. | EcoR1 Capital Oleg Nodelman | 3,346,301 | $61,472 | -8% | 6.42% |
| 3. | Bridger Management Roberto Mignone | 1,679,344 | $30,850 | -16% | 3.56% |
| 4. | Parkman Healthcare Partners Greg Martinez | 300,805 | $5,526 | +26% | 2.56% |
| 5. | Acuta Capital Partners Manfred Yu | 256,500 | $4,712 | -34% | 2.28% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $7.00 | 285,000 | Large Shareholder, Director | 285,000 | 2017-12-18 | Filing | |
| $3.63 | 16,500 | Officer, Director | 55,579 | 2016-11-15 | Filing | |
| $3.78 | 16,600 | Officer, Director | 39,079 | 2016-11-14 | Filing | |
| $3.29 | 4,170 | Officer | 19,800 | 2016-05-12 | Filing | |
| $3.29 | 530 | Officer | 15,630 | 2016-05-12 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $24.00 | 13,281 | Officer | 5,000 | 2020-05-11 | Filing | |
| $21.00 | 8,185 | Officer | 5,000 | 2020-05-05 | Filing | |
| $20.20 | 4,360 | Officer | 21,860 | 2020-05-04 | Filing | |
| $22.95 | 25,624 | Officer | 19,421 | 2020-04-20 | Filing | |
| $23.00 | 13,281 | Officer | 5,000 | 2020-04-20 | Filing |
| No. | Name | Shares | Value (x$1000) | % Port |
|---|---|---|---|---|
| 1. | 4,080,237 | $74,954 | 12.67% | |
| 2. | 6,963,135 | $127,913 | 5.5% | |
| 3. | 88,465 | $1,625 | 0.95% | |
| 4. | 668,124 | $12,273 | 0.7% | |
| 5. | 482,001 | $8,854 | 0.55% |
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