| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 10,900,000 | $375,941,000 | +3% | 4.86% |
| 2. | Slate Path Capital David Greenspan | 4,982,000 | $171,829,180 | -5% | 2.66% |
| 3. | Siren L.L.C. Raymond Debbane | 2,669,880 | $92,084,161 | 3.6% | |
| 4. | Driehaus Capital Richard Driehaus | 2,099,398 | $72,408,237 | 0.52% | |
| 5. | Arrowstreet Capital Peter Rathjens, Bruce Clarke And John Campbell | 2,081,689 | $71,797,454 | +3143% | 0.05% |