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Why Is AstraZeneca PLC (AZN) Among the Best Large-Cap Value Stocks to Buy in 2025?

We recently compiled a list of the 15 Best Large-Cap Value Stocks to Buy in 2025. In this article, we are going to take a look at where AstraZeneca PLC (NASDAQ:AZN) stands against the other large-cap value stocks.

Why is this Portfolio Manager Cautiously Optimistic?

The market outlook is as uncertain as it gets. On January 18, Robert Pavlik, senior portfolio manager at Dakota Wealth Management, appeared in an interview on Wealth at Yahoo Finance to share his market outlook, which happens to be rather optimistic or “cautiously optimistic.”

Pavlik shared that as the new administration takes over he is optimistic about how the market will play out in the near future. He added that the new government is expected to do some deregulation and cut corporate taxes, which are supposedly going to boost earnings despite inflation being a concern. He also explained why he was cautious earlier. He stated that the easing cycle was more uncertain and the new government was emphasizing tariffs earlier, however, as time has passed, Pavlik has grown to become more optimistic about the market.

He also expects the economy to grow, suggesting that the US is nowhere near a recession. In addition to that, Pavlik is confident that valuations are expected to ease, tariffs seem to be a “bargaining chip,” and mass deportations are “not going to happen.” In addition to that, he believes new energy policies to lower the price of oil and gas, resulting in lower costs incurred by firms across nearly every industry.

By the middle of 2025, Pavlik expects the Fed to be back issuing multiple rate cuts. Overall, he expects 2025 to be a solid year for equities, with expectations of the S&P 500 reaching 6,750, representing a 13-14% growth from January 18, 2025. While he agrees that in the near term, especially in the first 100 days of the new government, there are reasons to be slightly cautious, he remains confident that the new policies will work out as the market goes forward.

Speaking of inflation, Pavlik reiterated that the new energy policies will definitely push oil companies to produce more oil as a result of cost reductions. These cost reductions are expected to have a multiplier effect on grocery companies which will ultimately cater to inflationary pressures, added the portfolio manager. This coupled with his expectation of the Fed returning to its planned easing cycle will likely fuel shared investor sentiment and consumer confidence.

While the first 100 days of the new administration may be uncertain and volatile, there are some stocks known to have been stable through rough or smooth market conditions. That said, let’s take a look at the 15 best large-cap value stocks to buy in 2025.

Our Methodology

We used Finviz to look for companies operating in value sectors such as consumer defensive, financials, healthcare, and utilities. We only focused on companies with a market cap of more than $10 billion. We then examined the analyst upside surrounding 25 stocks and picked the 15 stocks with the highest upside as of January 20, 2025. We have also included the hedge fund sentiment around each stock.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 275% since May 2014, beating its benchmark by 150 percentage points (see more details here).

A pharmacy worker distributing prescription medicines to patientsreceiving treatment for oncology, cardiovascular, renal, metabolism and respiratory diseases.

AstraZeneca PLC (NASDAQ:AZN)

Analyst Upside as of January 20, 2025: 31%

Number of Hedge Fund Holders: 42

AstraZeneca PLC (NASDAQ:AZN) ranks seventh on our list of the best large-cap value stocks to buy in 2025. AstraZeneca is a pharmaceutical company headquartered in Cambridge, United Kingdom. In the third quarter of 2024, the company logged $39.18 billion in revenue, up by 19%. Of this, product revenue was $37.6 billion, accounting for most of the sales. For the fiscal year 2024, AstraZeneca PLC (NASDAQ:AZN) upgraded its revenue guidance to grow by a high-teen percentage.

AZN is positioned for long-term success, given it aims to make $80 billion in revenue by 2030 and register sustained growth ahead of 2030. The company expects to reach this parameter by launching at least 20 new medicines by 2030 and accelerating the processing of existing medicines. Beyond 2030, AstraZeneca PLC (NASDAQ:AZN) intends to invest in disruptive categories that will shape the future of healthcare such as cell therapy, gene therapy, and next-generation immunotherapy.

On January 20, Sachin Jain, an analyst from Bank of America Securities, reiterated a buy rating on the stock with a $91.70 price target. Jain gave a buy rating on the stock because AZN has displayed robust growth from key products. In addition to that, the analyst remains particularly optimistic about the company’s future growth potential and promising pipeline.

Overall AZN ranks 7th on our list of the best large-cap value stocks to buy in 2025. While we acknowledge the potential of AZN as an investment, our conviction lies in the belief that certain AI stocks hold greater promise for delivering higher returns, and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than AZN but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

READ NEXT: 20 Best AI Stocks To Buy Now and Complete List of 59 AI Companies Under $2 Billion in Market Cap.

Disclosure: None. This article is originally published at Insider Monkey.

The $250 Trillion AI Hype is Real. A few years from now, you’ll probably wish you’d bought this stock.

Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

When Jeff Bezos said that one breakthrough technology would shape Amazon’s destiny, even Wall Street’s biggest analysts were caught off guard.

Fast forward a year and Amazon’s new CEO Andy Jassy described generative AI as a “once-in-a-lifetime” technology that is already being used across Amazon to reinvent customer experiences.

At the 8th Future Investment Initiative conference, Elon Musk predicted that by 2040 there would be at least 10 billion humanoid robots, with each priced between $20,000 and $25,000.

Do the math. According to Musk, this technology could be worth $250 trillion by 2040.

Put another way, that’s roughly equal to:

  • 175 Teslas
  • 107 Amazons
  • 140 Metas
  • 84 Googles
  • 65 Microsofts
  • And 55 Nvidias

And here’s the wild part — this $250 trillion wave isn’t tied to one company, but to an entire ecosystem of AI innovators set to reshape the global economy.

It’s a leap so massive, it could reshape how businesses, governments, and consumers operate worldwide.

Even if that $250 trillion figure sounds ambitious, major firms like PwC and McKinsey still see AI unlocking multi-trillion-dollar potential.

How could anything be worth that much?

The answer lies in a breakthrough so powerful it’s redefining how humanity works, learns, and creates.

And this breakthrough has already set off a frenzy among hedge funds and Wall Street’s top investors.

What most investors don’t realize is that one under-owned company holds the key to this $250 trillion revolution.

In fact, Verge argues this company’s supercheap AI technology should concern rivals.

Before I reveal the details, let’s talk about how some of the richest people on the planet are positioning themselves.

  • Bill Gates sees artificial intelligence as the “biggest technological advance in my lifetime,” more transformative than the internet or personal computer, capable of improving healthcare, education, and addressing climate change.
  • Larry Ellison — through Oracle, is spending billions on Nvidia chips and partnering with Cohere to embed generative AI across Oracle’s cloud and apps.
  • Warren Buffett — not known for tech hype — says this breakthrough could have a ‘hugely beneficial social impact.

When billionaires from Silicon Valley to Wall Street line up behind the same idea — you know it’s worth paying attention to.

Even as we admire what Tesla, Nvidia, Alphabet, and Microsoft have built, we believe an even greater opportunity lies elsewhere…

But the real story isn’t Nvidia — it’s a much smaller company quietly improving the critical technology that makes this entire revolution possible.

And judging by what I’m hearing from both Silicon Valley insiders and Wall Street veterans…

This prediction might not be bold at all:

A few years from now, you’ll wish you’d owned this stock.

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Wall Street calls this $3 stock a “Melting Ice Cube.” They said the same thing about BTI before it returned 90%.

Dr. Inan Dogan

Dr. Ian Dogan

Co-Founder and Research Director at Insider Monkey

My name is Inan Dogan. I’m the co-founder and Research Director of Insider Monkey. I have an important message for you today.

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We alerted our subscribers, and BTI returned 90% in just 16 months.

Now if you had invested just $10,000 in BTI in June 2024, you’d be sitting on $19,000 in October 2025.

Today, we have identified a nearly identical pattern in a digital-first giant trading at $3.

While the market panics over a surface-level revenue decline, our PhD-led research shows management has actually surgically cut $100 million in waste to focus on high-margin growth.

This pattern is a hallmark of our 16.5% annual return track record. The current opportunity offers a 400% upside potential—dwarfing even our 90% BTI return.

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