RiverPark Advisors, an investment advisory firm and sponsor of the RiverPark family of mutual funds, released its “RiverPark Large Growth Fund” Q4 2025 investor letter. A copy of the letter can be downloaded here. The US stock market delivered modest gains in the quarter with the S&P 500 index (“S&P”) and the Russell 1000 Growth index (“RLG”) returning 2.6% and 1.1%, respectively. The Fund appreciated by 1.4% during the same period. For the full year, the Fund was up 13.3% vs. 17.4% and 18.6% gains, respectively, for the indexes. The performance in the Russell 1000 Growth Index was uneven. Market leadership remains concentrated, but underlying divergence has deepened. Investors preferred companies with durable earnings and progress in monetizing growth, especially in health care and parts of the AI value chain. The Fund is optimistic that its portfolio consists of attractively valued companies benefiting from strong growth trends and expected to generate significant cash flow. Please review the Fund’s top five holdings to gain insights into their key selections for 2025.
In its fourth-quarter 2025 investor letter, RiverPark Large Growth Fund highlighted Intuitive Surgical, Inc. (NASDAQ:ISRG) as one of its leading contributors. Intuitive Surgical, Inc. (NASDAQ:ISRG) is a leader in robotic-assisted surgery that develops, manufactures, and markets products for improving the quality of and access to minimally invasive care. On March 26, 2026, Intuitive Surgical, Inc. (NASDAQ:ISRG) stock closed at $468.55 per share. One-month return of Intuitive Surgical, Inc. (NASDAQ:ISRG) was -6.94%, and its shares lost 4.74% over the past 52 weeks. Intuitive Surgical, Inc. (NASDAQ:ISRG) has a market capitalization of $166.415 billion.
RiverPark Large Growth Fund stated the following regarding Intuitive Surgical, Inc. (NASDAQ:ISRG) in its fourth quarter 2025 investor letter:
“Intuitive Surgical, Inc. (NASDAQ:ISRG): ISRG shares appreciated in the fourth quarter after the company delivered strong Q3 results highlighting continued procedure growth and accelerating system placements. Procedure volumes rose in the mid-teens globally, with notable strength in general surgery and urology, while recurring instrument and accessory revenue grew faster than expectations. Management also reported that the early rollout of its next-generation robotic platform was tracking ahead of schedule, with utilization metrics trending positively across beta sites. Improved supply chain conditions and lower logistics costs contributed to better operating margins.
We view Intuitive Surgical as the clear leader in robotic-assisted surgery, with a deep installed base, high recurring revenue, and decades of clinical data supporting continued adoption. The company’s long runway for procedure penetration, next-generation platform upgrades, and expanding indications underpin durable revenue and earnings growth. With strong balance sheet flexibility and a best-in-class recurring revenue model, ISRG remains a high-quality compounder.”
Intuitive Surgical, Inc. (NASDAQ:ISRG) is not on our list of 40 Most Popular Stocks Among Hedge Funds Heading Into 2026. According to our database, 109 hedge fund portfolios held Intuitive Surgical, Inc. (NASDAQ:ISRG) at the end of the fourth quarter, up from 99 in the previous quarter. While we acknowledge the risk and potential of Intuitive Surgical, Inc. (NASDAQ:ISRG) as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than Intuitive Surgical, Inc. (NASDAQ:ISRG) and that has 10,000% upside potential, check out our report about this cheapest AI stock.
In another article, we covered Intuitive Surgical, Inc. (NASDAQ:ISRG) and shared a list of stocks Jim Cramer discussed. In addition, please check out our hedge fund investor letters Q4 2025 page for more investor letters from hedge funds and other leading investors.
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Disclosure: None. This article is originally published at Insider Monkey.
