Twist Bioscience Corporation (NASDAQ:TWST) Q1 2024 Earnings Call Transcript

Luke Sergott: Can you — I want to start talking about first on the increase in the OpEx spend. I know that, you’ve always talked about growing at slower than your revenue growth, but just incremental step-up through here throughout the year, like where is that investment going? And is it just to fill more commercialization on the Express Genes. Can you just give us some color?

Adam Laponis: I’m happy to step in on that one. And actually, in the G&A line specifically. It’s not the incremental ends on infrastructure, particularly around some of our IT and financial capabilities. It is we’re really focused on building out those capabilities right now. So we’ve made some choices around how we’re going to invest in that the scale not only for the current year, but future years depend as well.

Luke Sergott: Okay. That’s helpful. And then you talked about like some of the early learning’s from the elasticity that from the dynamic pricing. Talk about any trends that you’re seeing there, from types of orders or customers or how that’s kind of pacing out? And where the dynamic pricing is really starting to contribute to the margin if it’s going to create any lumpiness or anything throughout the year?

Emily Leproust: Yeah. Thank you. That’s a good question. So, we have been — now that we have a good number of debt assets. We’ve been deeply looking into the price sensitivity response care. So, looking at the access, what is the capacity of the day ends, what is the premium of the day, and on the way access, what is the percentage of customers that have that chose to purchase Express. And we actually see quite a — what you will expect as a response curve. So, at a very low of a high percentage of a premium you see saturation. And then you see kind of no response in between. So it’s an incredible view into the price elasticity that our customers have. And we are still able to see by geography and by industry types for instance, Biopharma versus Academic what question they have. So obviously we are going to refine our model overtime, but yeah, it’s quite encouraging to see that the outcome is what you would expect and then we will get from there.

Luke Sergott: Great. Thanks.

Operator: Thank you. Our next question comes from Matt Larew with William Blair. Your line is open.

Matt Larew: Hi. Good morning. First question is for Adam and just going back to Luke’s question on the SG&A investments you referenced sort of on the IT and financial capability side, are these what you view as kind of the only set of meaningful investments Adam that need to be made? Or are there multiple layers over the course of a couple of years? And sort of within that context, how do these investments or future investments affect the goal to get to adjusted EBITDA breakeven on the core business by the end of fiscal 2024?

Adam Laponis: No Matt. I think a great question. And I think a couple of comments here. In terms of the focus of the business and the priorities, it’s very clear to me and it’s been clear for them hopefully in our commentary as well. But the priority is around revenue growth margin expansion and cash management. So we’re never in a place where we need to go back to the markets for an equity raise in the future. And so that path to profitability is very much a key part of everything we’re doing and how we’re thinking about it. I haven’t provided the exact timing. I’m not giving guidance on when we’ll get to profitability. But I am saying that, in confidence we won’t be coming back to the market. And in terms of the investments, again, I’m going to lean on the factors week three.

I’m still getting my bearings. And I think about it pretty carefully right now is I don’t want to make any major changes in investment strategy. That’s not what we’re looking to do here. I want to make sure, we continue to see progress. And if you think about areas like supply chain for example, we’re the teams are laser focused on driving out costs throughout the system, supplier consolidation, in-sourcing, restaurant, inventory optimization. All of these things are getting easier, as we continue to scale. We gain leverage. So that the focus and momentum on that. And I want to make sure we’re balancing that any investment with those savings overtime. So my goal is very much still to keep a tab on any expansion the SG&A investment by making sure, we’re pacing and the incremental investments with the savings are driving in other areas of the business.

Hopefully that provides clarity.

Matt Larew: Yeah. That’s helpful. And then Emily, you referenced some potential new products being launched next week. And so the question is, you obviously have quite a bit of knowledge about what purchasers of DNA want and increasingly sort of what they’re willing to pay for as you think about moving into areas like RNA Synthesis, Express RNA. What do you know about what RNA customers might value differently than DNA customers? How are you sort of assessing the key attributes of what those products would need to look like relative to DNA? And it would you could extend that even things like proteins, IgG et cetera

Emily Leproust: Thank you, Matt. And so I spent a lot of time with customers and I think those are the two primary questions and then a bunch of secondary ones. The primary questions with customers as always and when and how much, but it’s always one point when will they get it and how much will it cost? And then, after that there’s a number of secondary questions around liquidity and support and packaging. And so there are some product features that you need to have for instance quality in order to be in business. But assuming that those are met it’s always about speed and cost. And that it’s really well we do the Twist’s brand as well that we are making. We’ve always been really good at cost and that comes from the silicon chip that gives us an advantage by using less reagents.

We’re able to have a lower cost base than our competitors. and so we’ve always been really good on the cost side. Historically I would say up until now of late 2022 were not great on speed. We are probably on par with others. But now that we’ve made the investment in speed is really becoming the second on strengths that we have not done and we’ll keep leveraging that that brand. So anything twisted. They are high quality product, very great customer experience and we can customize any packaging deliveries schedule that you want. And that’s all great. But most importantly it’s going to be fast. It may be a great price to enable your science. You’re going to get more shots on goal and that means that we’ll get all your budget because you choose us exclusively.

Matt Larew: Okay. Thank you.

Operator: Thank you. Our next question comes from Catherine Schulte with Baird. Your line is open.

Catherine Schulte: Hi. Thanks for the questions. Maybe first on NGS is what’s driving the sequential decline in your second quarter guidance. Are there any one-timers in the first quarter? I think you mentioned some large orders so there just any way to quantify those?

Emily Leproust: Maybe I add something for you as one of the reports — one of the number we report is the percentage of revenue NGS that comes from 10 customers. And as you can see it is a very meaningful number. And so when you have a number of big customers, it can be a little bit lumpy quarter-over-quarter, year-over-year is fine but quarter-to-quarter it can be lumpy. As you remember Q1 of last year was the opposite situation where we have some big customers and they delayed taking shipment. And so the solution for us is let’s go find more labs might. So we are going to — we are pushing on adding more and more of those top accounts and over time since we see smoother vessel. So we have great confidence for our view for the year. And at the same time, we are there to serve our customers and if some of those customers want shipment early or later, we always accommodated their needs to make sure that customer satisfactions is as high as possible.

Catherine Schulte: Okay. And then maybe on CapEx there’s a pretty decent step down versus your prior guide on a percentage basis. Can you just talk through what projects that are either being pushed out or just words savings are coming from?

Adam Laponis: This is Adam and I’ll be happy to take that one. If I look at it, I’m just as we went through after one quarter their budget, we were seeing some favorable stability in that. And we haven’t stopped through the projects we were initially starting. It’s just purely a reality. Have you refined the numbers we’re seeing a lower need for CapEx. I think the key message here in Wilsonville came online really fully for the first time in Q1 of this fiscal year. So even the depreciation for that, we still have a small step up as we get into Q2 on that. But we’re really excited about the capacity that brings. And I’m sure there will be minor things to continue to expand the capabilities and efficiency of the site. But we’re really focused on optimizing where we are this year.

Catherine Schulte: Okay. Thank you.

Operator: Thank you. Our next question comes from Puneet Souda with Leerink Partners. Your line is open.

Puneet Souda: Sorry if I missed that, this is Puneet from Leerink. First question maybe for Adam, I mean your orders increased by almost $6.5 million sequentially, but your guide is only up by the beat. Maybe just — could you talk a little bit about where these orders are coming from in terms of customer type, NGS, synbio, maybe just talk to us about that? And then the level of conservatism you have that you talked about, maybe Adam, just help us understand the level of conservatism kind of conservatism that you have versus the you know the step down that we are seeing an NGS in the second half. And then I have follow up for Emily.