Top Investors’ Stock Portfolio: 10 Mid-cap Stocks To Buy

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4. Jazz Pharmaceuticals plc (NASDAQ:JAZZ)

Market Capitalization: $9.96 billion

Number of Hedge Fund Holders: 49

Jazz Pharmaceuticals plc (NASDAQ:JAZZ) ranks among the mid-cap stocks to buy according to top investors. Truist Securities increased its price target for Jazz Pharmaceuticals plc (NASDAQ:JAZZ) to $230 from $220 on January 12, preserving a Buy rating on the company. The rise follows practice-changing results from the HERIZON-GEA trial, which Truist used to justify adjusting its Ziihera estimations higher.

In order to get a broad label for first-line gastroesophageal adenocarcinoma (GEA) as both doublet and triplet therapy with priority review, Jazz Pharmaceuticals plc (NASDAQ:JAZZ) executives intends to file a supplemental Biologics License Application (sBLA) in the initial half of 2026.

After clearance based on clinical data, Truist Securities anticipates strong commercial adoption, probable adoption in NCCN guidelines, over 90% prescriber crossover between GEA and biliary tract cancer (BTC), and compatibility of PD-1 inhibitor selection.

Jazz Pharmaceuticals plc (NASDAQ:JAZZ) is a biopharmaceutical company that develops treatments for serious illnesses. Its key products include Xywav, Xyrem, Epidiolex, Rylaze, Zepzelca, Defitelio, and Vyxeos.

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