Top 5 Best-Selling Cancer Drugs

3. Opdivo  

Total Sales: 17.8 billion  

Opdivo (nivolumab), widely used in cancer treatment, is often combined with Yervoy (ipilimumab). It demonstrates long-term efficacy in advanced renal cell carcinoma and adjuvant therapy of resected melanoma and esophageal/GEJ cancer. Opdivo’s cost, especially in combination therapy, raises considerations, prompting studies on its cost-effectiveness.