Supernus Pharmaceuticals, Inc. (NASDAQ:SUPN) Q4 2022 Earnings Call Transcript

Andrew Tsai: Makes sense. And then maybe the last question is I guess we can ask on the 2023 revenue guide, if we take out Trokendi, maybe it’s around 520 to 540, what would be the assumptions at the lower end, higher end? And it’s a pretty tight range. It seems like you do have visibility. But I guess also the root of the question is, do you think your initial guidance is provided in such a way that you could potentially raise your guidance throughout the year? Thanks.

Jack Khattar: I mean, in general, as a principle, and we like to provide a guidance that is our best guess at this time with the information that we have in providing the guidance for 2023. So our goal is always to do it in a reasonable way. That is, of course, achievable. We don’t like to miss guidance, but also we don’t like to be too conservative either. So you have to really be in a reasonable band providing the guidance. So to your question, when you back out Trokendi XR and you look at the remaining pieces, Oxtellar XR, APOKYN, GOCOVRI, for example, continue to be a growth product for us, and we’re happy with the growth that it delivered. And then you look at the other 3 products, I think you can get to a reasonable range on what Qelbree really is and how much Qelbree is as far as part of that guidance.

So we feel pretty comfortable with the ranges around the different pieces. And for the same reasons I mentioned today about Qelbree and how we’re very excited about its potential, the momentum the product has had a great start in 2023 so far. And we’re pretty happy with the different metrics that I talked about. So all in all, we think this guidance should be achievable. But only time will tell, and we’ll update you as time goes on.

Andrew Tsai: Very clear. Thank you.

Operator: Our next question will come from Annabel Samimy of Stifel. Your line is open.

Jack Padovano: This is Jack on for Annabel. Thanks for taking our questions. So two for us. First, regarding the patients on Qelbree, do you have any additional clarity on how many of those patients are newly diagnosed versus coming from stimulants? And have you noticed any differences between pediatric adult patients in terms of willingness to begin treatment with a non-stimulant compared to transitioning from a prior stimulant? And second, for some additional granularity on the GOCOVRI efforts. Growth has been decent so far, but do you have an idea on how much of this growth is a result from your improved messaging about the dual profile versus improved payer access? And what specifically is resonating most with physicians? Thanks.

Jack Khattar: Yes, starting with Qelbree as far as the source of the business or where are these patients primarily coming from, when we ask current prescribers of Qelbree, and we talk about that, I referenced that a little bit last year in a couple of quarters. Most of the patients in the top four reasons for why physicians are putting patients on the product is that these are patients who have issues with stimulants. And we mentioned that, that actually is very reassuring for us because we wanted Qelbree to be seen as an alternative, not just to other non-stimulants but actually an alternative for all patients in ADHD. And primarily those in the stimulant category because we know for a fact a lot of patients are out there are on the stimulants and they don’t need to be on stimulants or they don’t have to be on stimulants and put up with all the issues that stimulants bring as far as tolerability and safety and abuse of controlled substances and so forth.