Small Stocks, But Explosive: These 10 Firms Crushed The Market Last Week

Share prices of ten nano- and small-cap companies exploded last week, posting notable increases between 100 to 1,000 percent, outperforming the sluggish weekly performance of Wall Street’s major indices.

In this article, let us explore the 10 small but terrible companies that led last week’s charge, as well as the reasons behind their gains.

To come up with the list, we considered only the stocks with more than 5 million in trading volume. The list was based on their closing prices on May 30 and May 23, 2025.

10. BioLineRx Ltd. (NASDAQ:BLRX)

BioLineRx surged by 43.44 percent week-on-week as investors cheered the positive results from the single-arm pilot phase of the CheMo4METPANC Phase 2 combination clinical trial, which it was set to present at an ongoing oncology annual meeting.

In a statement, BioLineRx Ltd. (NASDAQ:BLRX) said that the CheMo4METPANC trial is evaluating its CXCR4 inhibitor motixafortide for the potential treatment of pancreatic cancer.

Updated results from the trial showed that four of 11 patients remained progression-free after more than a year, while two underwent definitive treatment for mPDAC, a highly aggressive, lethal form of pancreatic cancer. Another patient had complete resolution of all radiologically detected liver lesions, and one had a sustained partial response.

“The data that continue to emerge from the pilot phase of the CheMo4METPANC Phase 2 study are extremely encouraging,” said BioLineRx Ltd. (NASDAQ:BLRX) CEO Philip Serlin, saying that he was looking forward to the results of the ongoing randomized portion of the study.

9. Tian Ruixiang Holdings Ltd (NASDAQ:TIRX)

China-based insurer Tian Ruixiang Holdings Ltd (NASDAQ:TIRX) saw its share prices increase by 47 percent week-on-week as investor sentiment was buoyed by a share swap deal with an AI-driven hospital and health insurance risk management platform for $150 million.

In a statement, Tian Ruixiang Holdings Ltd (NASDAQ:TIRX) said that it is set to acquire 100 percent of the issued and outstanding shares of Ucare Inc. in exchange for more than 101 million of its shares at a par value of $0.025 each.

The transaction would make Ucare sellers the controlling owner of Tian Ruixiang Holdings Ltd (NASDAQ:TIRX), effectively owning 91.75 percent of the company, which would represent approximately 13.70 percent of its total voting power.

However, it remains unclear if the transaction would result in a potential backdoor listing.

Both parties expect the transaction to close by July 2025. Shares issued to the sellers will be held in escrow and released based on Ucare achieving a cumulative revenue target of at least RMB150 million over the three years post-closing.