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Septerna, Inc. (SEPN): Among the Best Rebound Stocks to Invest In Now

We recently compiled a list of the 10 Best Rebound Stocks To Invest In Now. In this article, we are going to take a look at where Septerna, Inc. (NASDAQ:SEPN) stands against the other rebound stocks.

The United States economy is in a constant state of flux. In recent weeks, moderated growth, evolving monetary policies, and significant trade developments have impacted the overall outlook for the economy. The Organisation for Economic Co-operation and Development (OECD) anticipates a deceleration in US economic growth, projecting a decrease from 2.6% in 2024 to 1.6% in 2025. This slowdown is expected to be mitigated by monetary policy easing, with policy interest rates projected to decline by an additional 1.5 percentage points by the end of 2025, aligning rates toward neutral levels. Contrastingly, Goldman Sachs offers a more optimistic outlook, forecasting a 2.5% growth in US GDP for 2025, surpassing the consensus estimate of 1.9%. Chief US Economist David Mericle emphasizes the diminishing recession fears, noting that inflation is trending back toward 2%, and the labor market has rebalanced but remains strong. However, potential policy changes, including increased tariffs and reduced immigration, could influence this trajectory.

Read more about these developments by accessing 10 Best AI Data Center Stocks and 10 Buzzing AI Stocks According to Goldman Sachs.

Recent trade policies have introduced uncertainties into the economic landscape. President Trump’s announcement of 25% tariffs on imports from Mexico and Canada, and 10% on Chinese imports, has led to swift retaliatory measures and heightened fears of a global trade war. Major stock indices, including Germany’s DAX, France’s CAC, and the UK’s FTSE 100, experienced declines. In the US, the Dow Jones, S&P 500, and Nasdaq futures indicated drops as well. Analysts express concerns that these tariffs could increase consumer prices, affect corporate profits, and potentially lead to recessions in both Mexico and Canada. Financial institutions such as JPMorgan, Deutsche Bank, and Goldman Sachs are revising their economic forecasts, considering potential court injunctions against the tariffs, and evaluating broader economic impacts, including inflation hikes and growth decreases.

Read more about these developments by accessing 30 Most Important AI Stocks According to BlackRock and Beyond the Tech Giants: 35 Non-Tech AI Opportunities.

To make our list of the best rebound stocks to invest in now, we ranked the most valuable stocks with a market cap greater than $300 million that are down 30% or more year-to-date. Out of these, we picked the top ten stocks with the highest number of hedge fund investors. Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 275% since May 2014, beating its benchmark by 150 percentage points (see more details here).

A scientist in a white lab coat measuring liquid in a beaker in the biotechnology lab.

Septerna, Inc. (NASDAQ:SEPN)

Number of Hedge Fund Holders: N/A  

Year-To-Date Decline in Share Price: 34.8%   

Septerna, Inc. (NASDAQ:SEPN) is a clinical-stage biotechnology company that discovers and develops G protein-coupled receptor oral small molecule product candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. In November last year, investment advisory JPMorgan initiated coverage of the stock with an Overweight rating and a price target of $38, citing the company’s platform for GPCR drug design. Notwithstanding manifold newly actionable GPCR targets, we see Septerna executing a highly attractive pipeline strategy, focused on validated targets in large established indications where an oral option offers a clear benefit to patients, the bank said in a note.

Overall SEPN ranks 10th on our list of the best rebound stocks to invest in. While we acknowledge the potential of SEPN as an investment, our conviction lies in the belief that some stocks hold greater promise for delivering higher returns, and doing so within a shorter timeframe. If you are looking for a stock that is more promising than SEPN but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

READ NEXT: 20 Best AI Stocks To Buy Now and Complete List of 59 AI Companies Under $2 Billion in Market Cap

Disclosure: None. This article is originally published at Insider Monkey.

AI, Tariffs, Nuclear Power: One Undervalued Stock Connects ALL the Dots (Before It Explodes!)

Artificial intelligence is the greatest investment opportunity of our lifetime. The time to invest in groundbreaking AI is now, and this stock is a steal!

AI is eating the world—and the machines behind it are ravenous.

Each ChatGPT query, each model update, each robotic breakthrough consumes massive amounts of energy. In fact, AI is already pushing global power grids to the brink.

Wall Street is pouring hundreds of billions into artificial intelligence—training smarter chatbots, automating industries, and building the digital future. But there’s one urgent question few are asking:

Where will all of that energy come from?

AI is the most electricity-hungry technology ever invented. Each data center powering large language models like ChatGPT consumes as much energy as a small city. And it’s about to get worse.

Even Sam Altman, the founder of OpenAI, issued a stark warning:

“The future of AI depends on an energy breakthrough.”

Elon Musk was even more blunt:

“AI will run out of electricity by next year.”

As the world chases faster, smarter machines, a hidden crisis is emerging behind the scenes. Power grids are strained. Electricity prices are rising. Utilities are scrambling to expand capacity.

And that’s where the real opportunity lies…

One little-known company—almost entirely overlooked by most AI investors—could be the ultimate backdoor play. It’s not a chipmaker. It’s not a cloud platform. But it might be the most important AI stock in the US owns critical energy infrastructure assets positioned to feed the coming AI energy spike.

As demand from AI data centers explodes, this company is gearing up to profit from the most valuable commodity in the digital age: electricity.

The “Toll Booth” Operator of the AI Energy Boom

  • It owns critical nuclear energy infrastructure assets, positioning it at the heart of America’s next-generation power strategy.
  • It’s one of the only global companies capable of executing large-scale, complex EPC (engineering, procurement, and construction) projects across oil, gas, renewable fuels, and industrial infrastructure.
  • It plays a pivotal role in U.S. LNG exportation—a sector about to explode under President Trump’s renewed “America First” energy doctrine.

Trump has made it clear: Europe and U.S. allies must buy American LNG.

And our company sits in the toll booth—collecting fees on every drop exported.

But that’s not all…

As Trump’s proposed tariffs push American manufacturers to bring their operations back home, this company will be first in line to rebuild, retrofit, and reengineer those facilities.

AI. Energy. Tariffs. Onshoring. This One Company Ties It All Together.

While the world is distracted by flashy AI tickers, a few smart investors are quietly scooping up shares of the one company powering it all from behind the scenes.

AI needs energy. Energy needs infrastructure.

And infrastructure needs a builder with experience, scale, and execution.

This company has its finger in every pie—and Wall Street is just starting to notice.

Wall Street is noticing this company also because it is quietly riding all of these tailwinds—without the sky-high valuation.

While most energy and utility firms are buried under mountains of debt and coughing up hefty interest payments just to appease bondholders…

This company is completely debt-free.

In fact, it’s sitting on a war chest of cash—equal to nearly one-third of its entire market cap.

It also owns a huge equity stake in another red-hot AI play, giving investors indirect exposure to multiple AI growth engines without paying a premium.

And here’s what the smart money has started whispering…

The Hedge Fund Secret That’s Starting to Leak Out

This stock is so off-the-radar, so absurdly undervalued, that some of the most secretive hedge fund managers in the world have begun pitching it at closed-door investment summits.

They’re sharing it quietly, away from the cameras, to rooms full of ultra-wealthy clients.

Why? Because excluding cash and investments, this company is trading at less than 7 times earnings.

And that’s for a business tied to:

  • The AI infrastructure supercycle
  • The onshoring boom driven by Trump-era tariffs
  • A surge in U.S. LNG exports
  • And a unique footprint in nuclear energy—the future of clean, reliable power

You simply won’t find another AI and energy stock this cheap… with this much upside.

This isn’t a hype stock. It’s not riding on hope.

It’s delivering real cash flows, owns critical infrastructure, and holds stakes in other major growth stories.

This is your chance to get in before the rockets take off!

Disruption is the New Name of the Game: Let’s face it, complacency breeds stagnation.

AI is the ultimate disruptor, and it’s shaking the foundations of traditional industries.

The companies that embrace AI will thrive, while the dinosaurs clinging to outdated methods will be left in the dust.

As an investor, you want to be on the side of the winners, and AI is the winning ticket.

The Talent Pool is Overflowing: The world’s brightest minds are flocking to AI.

From computer scientists to mathematicians, the next generation of innovators is pouring its energy into this field.

This influx of talent guarantees a constant stream of groundbreaking ideas and rapid advancements.

By investing in AI, you’re essentially backing the future.

The future is powered by artificial intelligence, and the time to invest is NOW.

Don’t be a spectator in this technological revolution.

Dive into the AI gold rush and watch your portfolio soar alongside the brightest minds of our generation.

This isn’t just about making money – it’s about being part of the future.

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A New Dawn is Coming to U.S. Stocks

I work for one of the largest independent financial publishers in the world – representing over 1 million people in 148 countries.

We’re independently funding today’s broadcast to address something on the mind of every investor in America right now…

Should I put my money in Artificial Intelligence?

Here to answer that for us… and give away his No. 1 free AI recommendation… is 50-year Wall Street titan, Marc Chaikin.

Marc’s been a trader, stockbroker, and analyst. He was the head of the options department at a major brokerage firm and is a sought-after expert for CNBC, Fox Business, Barron’s, and Yahoo! Finance…

But what Marc’s most known for is his award-winning stock-rating system. Which determines whether a stock could shoot sky-high in the next three to six months… or come crashing down.

That’s why Marc’s work appears in every Bloomberg and Reuters terminal on the planet…

And is still used by hundreds of banks, hedge funds, and brokerages to track the billions of dollars flowing in and out of stocks each day.

He’s used this system to survive nine bear markets… create three new indices for the Nasdaq… and even predict the brutal bear market of 2022, 90 days in advance.

Click to continue reading…