Revolution Medicines Receives FDA Breakthrough Therapy Designation for Elironrasib for Lung Cancer

Revolution Medicines Inc. (NASDAQ:RVMD) is one of the best upside stocks to invest in now. Earlier on July 23, Revolution Medicines announced that the US FDA granted Breakthrough Therapy Designation to elironrasib (RMC-6291), its RAS(-ON) G12C-selective inhibitor. The designation is for treating adult patients with KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer/NSCLC who have already undergone chemotherapy and immunotherapy but have not yet been treated with a KRAS G12C inhibitor.

The designation aims to expedite the development and review of the drug, which addresses a significant unmet medical need. It was based on promising data from the Phase 1 RMC-6291-001 clinical trial. In the trial, elironrasib monotherapy showed competitive antitumor activity, a compelling objective response rate, and progression-free survival in patients with advanced KRAS G12C solid tumors.

Revolution Medicines Receives FDA Breakthrough Therapy Designation for Elironrasib for Lung Cancer

A researcher poring over test results, illustrating the breakthrough potential of biotechnology.

Elironrasib is an innovative inhibitor that selectively binds to the oncogenic RAS(-ON) form of the RAS G12C variant. This variant is a driver in ~12% of NSCLC cases. Revolution Medicines is currently exploring elironrasib as a monotherapy and in combination with other treatments. KRAS mutations are found in nearly 30% of NSCLC cases, with KRAS G12C being the most common subtype. Currently, there are no fully FDA-approved RAS-targeted inhibitors for patients with KRAS G12C NSCLC.

Revolution Medicines Inc. (NASDAQ:RVMD) is a clinical-stage precision oncology company that develops novel targeted therapies for RAS-addicted cancers.

While we acknowledge the potential of RVMD to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than RVMD and that has 100x upside potential, check out our report about this cheapest AI stock.

READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now.

Disclosure: None. This article is originally published at Insider Monkey.