Johnson & Johnson’s (JNJ) IMAAVY Demonstrates Superior gMG Control

Johnson & Johnson (NYSE:JNJ) is one of the 12 stocks that will make you rich in 10 years. On June 23, J&J announced new data from an indirect treatment comparison (ITC) study. The data show that the company’s drug, IMAAVY (nipocalimab-aahu), demonstrated consistent and sustained disease control in patients with generalized myasthenia gravis (gMG) compared to other approved FcRn blockers. The findings were presented at the European Academy of Neurology (EAN) 2025 Congress in Helsinki, Finland.

Johnson & Johnson’s (JNJ) IMAAVY Demonstrates Superior gMG Control

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According to the findings, IMAAVY showed a comparable onset of symptom relief at Week 1. The drug demonstrated consistent and sustained disease control over multiple timepoints up to 24 weeks. More importantly, IMAAVY showed greater or statistically significant improvement in Myasthenia Gravis Activities of Daily Living (MG-ADL) scores compared to the published Phase 3 data of other FcRn blockers.

The drug received FDA approval on April 30, 2025, for adults and pediatric patients aged 12 and older with anti-AChR or anti-MuSK antibody-positive gMG. This makes IMAAVY the first and only FcRn blocker approved for both antibody types, covering ≥90% of antibody-positive gMG patients.

Johnson & Johnson (NYSE:JNJ) is a global healthcare company. It develops, manufactures, and sells pharmaceuticals and medical devices through two main segments: Innovative Medicine and MedTech. Its key pharmaceutical products include Darzalex, Stelara, Tremfya, and Carvykti, while its MedTech offerings span surgical technologies, orthopedics, and vision care.

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