In this article, we will discuss: Growth Stock Portfolio: 12 Stock Picks By Cathie Wood.

After a severe 2022 decline, Cathie Wood’s flagship innovation fund witnessed a dramatic comeback through 2025, climbing 87.1% in the year ending in September 2025 and tripling over three years, according to a Forbes report on October 22, 2025. The fund managed $8.3 billion, down from $17 billion at the end of 2020, and was still roughly 42% behind its February 2021 peak after the comeback, showing persistent investor outflows. At the time, Wood stated that concerns about an AI-driven bubble were unfounded, stating that the businesses that are investing in artificial intelligence are some of the most profitable companies in the world. Wood also stated that the performance is not leveling out at all.

The return came after significant losses, including a 67% drop in 2022, when prior bets on smaller, innovation-driven businesses were negatively impacted by supply-chain interruptions and soaring rates. Wood later acknowledged those challenges but claimed a more favorable US policy environment, including deregulation and tax cuts under President Donald Trump, assisted her long-term approach. She remarked that the amount of deregulation is astounding. As of late 2025, three-year returns exceeded the overall market, but five-year performance was still poor, exposing the fund’s volatility.

Recently, TheStreet reported on January 23, 2026, that Cathie Wood made her first cryptocurrency-related purchases of the year. The purchases amounted to almost $9.4 million, as per ARK’s daily trade disclosures.

With that said, here are the Growth Stock Portfolio: 12 Stock Picks By Cathie Wood.

Our Methodology

To curate our list of billionaire Cathie Wood’s 12 growth stock picks, we scanned ARK Investment Management’s Q3 2025 13F filings, using Insider Monkey’s 13F database. We picked stocks with an average 5-year revenue growth of over 20% for our list. We have also mentioned the number of hedge fund holders for each stock using Insider Monkey’s database of hedge funds as of Q3 2025. The stocks are ranked in ascending order of their average 5-year revenue growth.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 427.7% since May 2014, beating its benchmark by 264 percentage points (see more details here).

12. Block, Inc. (NYSE:XYZ)

Average 5-Year Revenue Growth: 41.43%

Number of Hedge Fund Holders: 64

ARK Investment Management’s Stake Value: $193,207,725

Block, Inc. (NYSE:XYZ) is part of the Growth Stock Portfolio.

Before the company’s quarterly reports, TheFly reported on January 14, 2026, that Piper Sandler reduced its price objective for Block, Inc. (NYSE:XYZ) from $55 to $51. It kept an Underweight rating on the stock.

On the other hand, Truist reaffirmed a Hold rating on Block, Inc. (NYSE:XYZ) and boosted its price objective from $68 to $72 on January 20, 2026. Although the analyst anticipates strong fourth-quarter results, he warns that volume-related beats may be limited by more challenging year-over-year comparisons. Truist notes that certain management teams may modify the initial 2026 projection downward to reset Street expectations, but he is still upbeat about the FinTech group as a whole throughout 2026.

In the latest quarter, the firm boosted its full-year outlook to $10.2 billion gross profit in 2025, up from $10.2 billion last quarter. Moreover, Block, Inc. (NYSE:XYZ) announced net income of $461.54 million, or 74 cents per share, a considerable increase over last year’s net income of $283.75 million, or 45 cents per share.

Block, Inc. (NYSE:XYZ) offers merchants payment services and other related services. The company also established Cash App, a person-to-person payment network.

11. Natera, Inc. (NASDAQ:NTRA)

Average 5-Year Revenue Growth: 41.75%

Number of Hedge Fund Holders: 70

ARK Investment Management’s Stake Value: $143,680,703

Natera, Inc. (NASDAQ:NTRA) is part of the Growth Stock Portfolio. 

Natera, Inc. (NASDAQ:NTRA) announced preliminary fourth-quarter 2025 revenue of $660 million, exceeding the average forecast of $577.62 million, as reported by TheFly on January 12, 2026. Revenue for the entire year of 2025 was $2.3 billion, above the $2.22 billion estimate. Approximately 923,600 tests were processed in Q4, a 17% surge from 792,800 in Q4 2024. The total number of tests processed in FY25 was approximately 3,525,500, up 15% from 3,064,600 in 2024. CEO Steve Chapman noted record gains in the areas of women’s health, organ health, and oncology. He noted substantial spikes in volume, revenue, and gross margins and expressed confidence in the company’s ongoing growth through 2026.

On January 7, 2026, TD Cowen maintained its Buy recommendation and increased its price goal for Natera, Inc. (NASDAQ:NTRA) from $240 to $280. The company noted that the corporation’s fundamentals are still strong, citing solid Q4 earnings and a promising 2026 outlook for the diagnostics industry.

Natera, Inc. (NASDAQ:NTRA) is a research and diagnostic firm that uses exclusive molecular and bioinformatics technology.