Exact Sciences Corp (EXAS) Stock: D E Shaw Slightly Lowers Its Stake

Page 4 of 6 – SEC Filing

Item 1.
(a) Name of Issuer
Exact Sciences Corporation
(b) Address of Issuer’s Principal Executive Offices
441 Charmany Drive
Madison, WI 53719  
Item 2.
(a) Name of Person Filing
D. E. Shaw & Co., L.P.
David E. Shaw  
(b) Address of Principal Business Office or, if none, Residence
The business address for each reporting person is:
1166 Avenue of the Americas, 9th Floor
New York, NY 10036
(c) Citizenship
D. E. Shaw & Co., L.P. is a limited partnership organized under the laws of the state of Delaware.
David E. Shaw is a citizen of the United States of America.
(d) Title of Class of Securities
Common stock, par value $0.01
(e) CUSIP Number
30063P105
Item 3. If this statement is filed pursuant to Rule 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:  
Not Applicable 
Item 4. Ownership  

As of September 27, 2016:

(a) Amount beneficially owned:

D. E. Shaw & Co., L.P.:

5,410,030 shares

This is composed of (i) 3,130,570 shares in the name of D. E. Shaw
Valence Portfolios, L.L.C., (ii) 57,100 shares that D. E. Shaw Valence Portfolios, L.L.C. has the right to acquire through the
exercise of listed call options, (iii) 2,162,850 shares in the name of D. E. Shaw Oculus Portfolios, L.L.C., (iv) 26
shares in the name of D. E. Shaw Asymptote Portfolios, L.L.C., and (v) 59,484 shares under the management of D. E. Shaw
Investment Management, L.L.C.

David E. Shaw:

5,410,030 shares

This is composed of (i) 3,130,570 shares in the name of D. E.
Shaw Valence Portfolios, L.L.C., (ii) 57,100 shares that D. E. Shaw Valence Portfolios, L.L.C. has the right to acquire through
the exercise of listed call options, (iii) 2,162,850 shares in the name of D. E. Shaw Oculus Portfolios, L.L.C., (iv) 26 shares
in the name of D. E. Shaw Asymptote Portfolios, L.L.C., and (v) 59,484 shares under the management of D. E. Shaw Investment Management,
L.L.C.

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