D. E. Shaw Stock Portfolio: Top 5 Stocks to Buy

3. Palantir Technologies Inc. (NASDAQ:PLTR)

D. E. Shaw’s Stake: $1.7 Billion

Compared to other top stocks in the D. E. Shaw portfolio, Palantir Technologies Inc. (NASDAQ:PLTR) is a relatively recent addition. The hedge fund first disclosed a stake in the company back in the first quarter of 2021, merely months after the public debut of the software firm that is now making waves across the stock market. This holding comprised just 600,000 shares then, but has grown following the initial purchase. In the second quarter of 2023, D. E. Shaw owned nearly 30 million in the company. The position has been reduced steadily following this high. Filings for the fourth quarter of 2025 that the hedge fund owned 9.7 million shares in the company, up 6% compared to filings for the previous quarter.

Palantir Technologies Inc. (NASDAQ:PLTR) has become one of the most polarizing yet heavily accumulated stocks in the hedge fund world. Hedge funds seem to be pivoting their thesis from Palantir as a government contractor to a commercial powerhouse. In the fourth quarter of 2025, US commercial revenue for the firm skyrocketed 137% year-over-year. Palantir’s Artificial Intelligence Platform has moved from experimental bootcamps to full-scale production. Funds are betting on management’s 2026 guidance, which calls for US commercial revenue to exceed $3.14 billion, a growth rate of at least 115%.